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- Vincristine could affect the activity of p38 MAPK in gastric cancer cell SGC7901 and multidrug resistant cell SGC7901/VCR. p38MAPK信號轉導途徑可能與長(cháng)春新堿的抗腫瘤活性相關(guān) ,腫瘤細胞內 p38MAPK對長(cháng)春新堿刺激的反應速度可能與胃癌長(cháng)春新堿耐藥相關(guān)
- Human bladder transitional cell cancer BIU 87 cells and multidrug resistant BIU 87/ADM cells were treated with daunorubicin (DNR) combined with JSB 1 and CsA alone or together and with JSB 1 and verapamil(Ver) alone or together. 為了證實(shí)抗P?糖蛋白（P?gp）單克隆抗體協(xié)同環(huán)孢素A（CsA）逆轉人膀胱癌耐藥細胞亞株的抗藥性以及建立能有效地克服MDR的治療方案，對人膀胱移行細胞癌BIU?87細胞系和BIU?87/ADM耐藥細胞亞株經(jīng)柔紅霉素（DNR）與抗P?gp單克隆抗體JSB?1和單獨或聯(lián)合CsA；
- During the development of MDR, epithelial to mesenchymal transition induced by Twist may be related to the enhanced invasion and metastatic potential of multidrug resistant breast cancer cells MCF-7/ADR. 在多藥耐藥乳腺癌細胞MCF-7/ADR中,其侵襲力增強可能與Twist介導的EMT發(fā)生有關(guān)。
- Objective To study the effective surgical way for serious relapse multidrug resistant bacillary cavitary pulmonary tuberculosis. 目的尋找通過(guò)外科手段治療內科無(wú)法根治的復治耐多藥菌陽(yáng)重癥空洞型肺結核的有效途徑。
- We summarized the structure,function,distribution,retroconversion,and detect method of the multidrug resistant gene. 現對多藥耐藥基因的結構、功能、表達、逆轉及其檢測手段等方面做一綜述。
- Multidrug resistant tuberculosis, or MDR-TB, will not get better with antibiotics normally used for tuberculosis. 多藥耐受性肺結核，即MDR-TB，用于通常肺結核的抗生素不能使其轉好。
- Kruh GD, Cb an A, Myers K et al. Expression complementary DNA transfer establishes map as a multidrug resistance gene[J] ,Cancer Res, 1994,54:1649. 張強;施作霖;陳梓甫.;腎細胞癌對化療藥物的多藥耐藥機制及其逆轉[J]
- Tetrandrine, neferine and dauricine showed obvious potenitiation of vincristine induced apoptosis in the human mammary MCF 7 multidrug resistant cells. 粉防己堿、甲基蓮心堿和蝙蝠葛堿均有明顯的增強長(cháng)春新堿誘導人乳腺癌MCF 7多藥耐藥細胞的凋亡作用
- Obsjective:To observe the reversal effect of Sangen Mixture(SGM) in multidrug resistant(MDR) cell lines K562/ADR and K562/VCR. 目的:研究三根制劑對多藥耐藥(MDR)細胞株的逆轉作用。
- Multidrug resistance (MDR) is the most common cause in the failure of cancer chemotherapy.Drug transporters play an important role in multidrug resistance in cancer. 多藥耐藥性(MDR)是腫瘤化療失敗的最常見(jiàn)原因,藥物轉運蛋白在腫瘤多藥耐藥性中產(chǎn)生了重要的作用。
- A significant impediment to the success of cancer chemotherapy is multidrug resistance (MDR)and this could be attributable to concomitance of multiple intricate mechanisms. 腫瘤多藥耐藥(MDR)是導致腫瘤化療失敗的主要原因之一,是多種復雜機制共同作用的結果。
- Cao J G,Tang X Q,Zhou H,et al.Reveral of Multidrug Resistance by neferine in adriamycin resistant human breast cancer cell line MCF7/ ADM[J].The Chinese睪erman J Clin Oncol,2004,3(2):9396. 唐小卿;曹建國;馮鑒強.;甲基蓮心堿對耐阿霉素人乳腺癌細胞凋亡抗性的影響[J]
- The chemosensitivity of multidrug resistant cell MCF-7Adr and drug sensitive cell MCF-7WTto doxorubicin,vincristine and colchicine was tested by MTT assay. 用MTT方法測定了多藥抗藥細胞MCF－7Adr及其敏感細胞MCF－7WT對阿霉素、長(cháng)春新堿、秋水仙堿的化學(xué)敏感性。
- On the recent base of research about dietary fiber in all the world, this paper summarize the function of resist cancer and the function of controlling the metabolize of carcinogens. 該文在對近年國內外有關(guān)膳食纖維研究文獻的研究基礎上,總結膳食纖維在抗腫瘤方面機理及對食品中致癌物代謝影響。
- Objective: To investigate the differentiation of multidrug resistant human leukemia cell line K562/ADM induced by cyclic adenosine monophosphate (cyclic AMP, cAMP). 目的:研究環(huán)腺苷酸(cyclicadenosinemonophosphate,cAMP)對人白血病多藥耐藥K562/ADM細胞的誘導分化作用。
- Flow cytometry was used to detect theexpression of HLA-l, HLA-2, B7-l, B7-2 in parent cell lines (COC1 andSKOV3 ) and multidrug resistant cell sublines (COCI/DDP andSKOV3/Adr). 運用流式細胞儀技術(shù)檢測了各種不同細胞亞株的HLA-1、HLA-2、B7-1、B7-2的表達。 結果：耐藥亞株COC1/DDP、SKOV_3/Adr和親本株COC1、SKOV_3的N-GSLs表達有差異，COC1/DDP、SKOV_3/Adr的CMH表達較COC1、SKOV_3強。
- Methods 104 cases of serious relapse multidrug resistant bacillary cavitary pulmonary tuberculosis were cured by cleaning cavity operation from 1981 to 1998. 方法1981-1998年6月采用空洞清除術(shù)治療復治耐藥空洞型肺結核104例。
- Meticillin-resistant staphylococcus aureus (MRSA) is transmissible and multidrug resistant, which made hospital infection rate of it increased yearly and transmitted rapidly. 耐甲氧西林金黃色葡萄球菌(MRSA)具有易傳播、多重耐藥的特性,使得醫院獲得性MRSA感染率逐年上升且傳播迅速、治療困難。
- Objective To investigate the restoration of the subcellular distribution of daunorubicin in the P glycoprotein mediated multidrug resistant cell line K562/ADR by quercetin. 目的研究槲皮素處理前后柔紅霉素(DNR)在耐藥細胞株K562/ADR亞細胞結構的不同分布。
- Objective: To investigate the inhibitory effect of ampelopsin (AMP) combined with adriamycin (ADR) on growth of human leukemia multidrug resistant cell line K562/ADR. 目的：研究蛇葡萄素與阿霉素合用對人白血病多藥耐藥細胞株K562/ADR增殖的抑制作用及其機制。
