Human bladder transitional cell cancer BIU 87 cells and multidrug resistant BIU 87/ADM cells were treated with daunorubicin (DNR) combined with JSB 1 and CsA alone or together and with JSB 1 and verapamil(Ver) alone or together.
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- 為了證實(shí)抗P?糖蛋白(P?gp)單克隆抗體協(xié)同環(huán)孢素A(CsA)逆轉人膀胱癌耐藥細胞亞株的抗藥性以及建立能有效地克服MDR的治療方案,對人膀胱移行細胞癌BIU?87細胞系和BIU?87/ADM耐藥細胞亞株經(jīng)柔紅霉素(DNR)與抗P?gp單克隆抗體JSB?1和單獨或聯(lián)合CsA;