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- Objective To clarify the role of a cell cycle regulator, cyclin D1 and CDK6 in patients with gastric carcinoma. 目的檢測細胞周期蛋白D1(cyclin D1)和細胞周期蛋白質(zhì)依賴(lài)激酶6(CDK6)在胃癌組織中的表達情況,分析其表達與胃癌的臨床病理因素和預后之間的關(guān)系。
- Genes involved in transcription, RNA processing, and cell cycle regulation were particularly affected. 這些受影響的基因主要基因涉及轉錄、RNA加工細胞周期調控等過(guò)程。
- The isoform CDK11p58 is specifically translated in G2/M phase and has much relation with cell cycle regulation. CDK11p58特異地在G2/M 期表達，和細胞周期的調節有著(zhù)密切的聯(lián)系。
- Many researches show that Skp2 can interact with many cell cycle regulating factors including p27, and lead to their ubiquitination and degeneration. Skp2是F-box蛋白家族的一員。研究發(fā)現，Skp2可與包括p27在內的多種細胞周期調控因子相互作用，導致它們的泛素化降解。
- The transcription factor,E2F,playing a critical role in cell cycle regulation,is involved in the pathophysiological process of restenosis. 2F是調控細胞周期進(jìn)程一個(gè)關(guān)鍵的轉錄因子,而且在血管再狹窄的病理過(guò)程中也起著(zhù)非常重要的作用。
- In summary, we here report that cyclin D3/CDK11p58 signaling is involved in the transcriptional regulation in eukaryotic cells as well as the cell cycle regulation. 綜上所述，我們發(fā)現cyclin D3/CDK11p58信號途徑除能調控細胞周期外，也參與了真核細胞的轉錄調控。
- Data from this study indicate that the inhibition of p15INK4B and p21WAF1/cip1 may be one of the mechanisms by which HDAC3 participates in cell cycle regulation and oncogenesis. 干涉質(zhì)粒能誘導p15INK4B基因表達活性的升高，而對p21WAF1/cip1的表達沒(méi)有什么影響。本研究表明去乙?；?可能是通過(guò)抑制p15INK4B和p21WAF1/cip1這種方式來(lái)參與周期調控和癌癥發(fā)生的。
- Research indicated that PI3K and MAPK signal pathways were associated with biological behaviors such as cell migration, inflammation, cell proliferation and cell cycle regulation. 已有的研究表明PI3K和MAPK信號傳導通路參與了細胞遷移、炎癥反應、細胞增殖和細胞周期調控等一系列過(guò)程,在腎組織纖維化的發(fā)生發(fā)展中發(fā)揮重要作用。
- The pedal of a cycle is attached to a crank. 自行車(chē)的踏板與曲柄相連。
- Objective To analyze the correlation of cell cycle regulation factors Cyclin D1, CDK. 4, P1 6 protein and p16 gene expression with clinicopathologic features and the prognosis in colorectal carcinoma. 目的 探討細胞周期調控因子Cyclin D1、CDK4、P16蛋白及p16基因表達與大腸癌的臨床病理特征及預后的關(guān)系。
- In fact, as a specific molecular chaperone, HSP90 proteins are possibly involved in many important physiological processes such as signal transduction, cell cycle regulation and hormone response. 事實(shí)證明，作為一種特異的分子伴侶，HSP90除在細胞正常生長(cháng)和應急保護中具有重要生理功能外，還與信號傳導、細胞周期調控、激素應答等細胞內重要生理過(guò)程有關(guān)。
- In order to build up a gastric carcinoma cell expressing human cyclin G2 gene stably, a useful tool for the research on the function of cyclin G2 in gastric carcinoma cell cycle regulation was made. 應用脂質(zhì)體基因轉染技術(shù)建立穩定表達cyclin G2基因的胃癌克隆細胞，為深入研究cyclin G2在胃癌細胞周期調控的作用和機制提供理想的生物學(xué)模型。
- It's easier to cycle with the wind behind you. 順風(fēng)騎車(chē)省力。
- A unit of frequency equal to one cycle per second. 赫茲頻率的單位，等于每秒一周
- The seasons of the year make a cycle. 一年四季構成一個(gè)循環(huán)。
- The business cycle experienced a sudden down. 商業(yè)周期經(jīng)歷了突然的蕭條。
- This is the cycle of economic booms and slumps. 這是經(jīng)濟繁榮和經(jīng)濟蕭條的周期變化。
- Cycle across America? Sounds a bit dodgy to me. 騎自行車(chē)橫越美國? 聽(tīng)起來(lái)有些冒險。
- The pedals of a cycle are attached to a crank. 自行車(chē)的踏板與曲柄相連。
- The pedals of a cycle are attached to the crank. 自行車(chē)的踏板與曲柄相連。
