Data from this study indicate that the inhibition of p15INK4B and p21WAF1/cip1 may be one of the mechanisms by which HDAC3 participates in cell cycle regulation and oncogenesis.
英
美
- 干涉質(zhì)粒能誘導p15INK4B基因表達活性的升高，而對p21WAF1/cip1的表達沒(méi)有什么影響。本研究表明去乙?；?可能是通過(guò)抑制p15INK4B和p21WAF1/cip1這種方式來(lái)參與周期調控和癌癥發(fā)生的。
