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- 抗Fas單抗anti-Fas monoclonal antibody
- 方法小兒急淋白血病細胞分別與Bcl?2反義脫氧寡核苷酸、抗Fas單抗培養，或與兩者一起培養，再分別定量檢測其凋亡細胞。Methods The percentage of apoptotic cells was detected after childhood ALL cells were incubated with Bcl 2 ASON, anti Fas MoAb or with both of them, respectively.
- 5 -FU、阿霉素能增加GRC- 1腎癌細胞株Fas表達并促進(jìn)Fas單抗誘導的腎癌細胞的凋亡。5-FU and ADR increased the Fas expression in GRC-1 RCC cell line and enhanced the apoptosis of GRC-1 cells induced by anti-Fas monoclonal antibody (CH11).
- 經(jīng) pcDNA3 Fas真核表達載體轉染的卵巢癌細胞Fas基因表達及對Fas單抗誘導凋亡的敏感性均有不同程度提高。Transfection of ovarian carcinoma cells with the eukaryotic vector pcDNA3 Fas enhanced cell surface expression of Fas gene and induced susceptibility to Fas antibody mediated apoptosis.
- 結論制備的可溶性抗Fas?Fab抗體具有抗Fas抗體的特異性,為進(jìn)一步的研究奠定了基礎。Anti Fas Fab phage antibody displaying on phage surface and soluble anti Fas Fab showed specific binding activity to Fas by ELISA. Conclusion The successful preparation of anti Fas Fab antibody paved a way for further study and application.
- 抗Fas抗體Anti-Fas antibody
- 目的：研究抗Fas抗體對人腎小球系膜細胞的致凋亡作用，探討Fas?FasL在腎臟損傷中的作用。Objective:To investigate the mechanism inducing apptosis of human glomerular mesangial cells (Mcs) by anti Fas antibody.
- 抗Fas抗體誘導維甲酸分化后的髓母細胞瘤細胞凋亡All-trans retinoic acid sensitizes human medulloblastoma cells Med-3 to anti-Fas antibody mediated apoptosis
- 單抗monoclonal antibody
- 用重組人Fas抗原進(jìn)行4輪篩選,得到100%的富集,說(shuō)明Fas重組抗原富集了抗Fas?Fab噬菌體抗體,經(jīng)ELISA檢測均有抗Fas抗體的特異性。The phage displaying antibody fragments were subjected to four rounds of panning with recombinant Fas antigen at solid phase. The eluted phage was enriched for nearly 100 fold and the percent of recombinant clones increased from 27%25 to 100%25 after four rounds of panning.
- 抗Fas錘頭狀核酶阻抑小鼠急性粒-單核白血病細胞免疫逃逸的研究Depressing the Immune Escape of Acute Myelomonocytic Leukemia via an Anti-Fas Ribozyme
- 5a8單抗monoclonal antibody to CD4,5a8<接觸HIV后的預防藥>
- VP1單抗Monoclonal antibody against VP1 protein
- 17-LA單抗monoclonal antibody 17-LA<胰腺癌治療藥>
- CD45單抗CD45 monoclonal antibodies<防器官移植排異藥>
- PM-81單抗monoclonal antibodies PM-81<白血病治療輔助藥>
- 阿昔單抗Abciximab
- 埃巴單抗Edobacomab
- 貝伐單抗bevacizumab<免疫調節藥>
- 比伐單抗bivatuzumab<免疫調節藥>
