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- Short Tandem Repeat in PLA2G4C gene, which can be screened from blood samples, relates to the pathogenesis of glioma. PLA2G4C的短串聯(lián)重復序列多態(tài)性與膠質(zhì)瘤的發(fā)病有一定關(guān)系,并可通過(guò)血液標本進(jìn)行此多態(tài)性的篩查。
- Objective:To analyze the genetic polymorphism of 9 short tandem repeat(STR) loci on chromosome 7p14-15 in Northeastern China Han population. 目的:分析東北漢族人群中7p14-15區域內9個(gè)短串聯(lián)重復序列(STR)位點(diǎn)的遺傳多態(tài)性。
- Methods The authors used a set of five Y-specific STR loci which were tetrameric tandem repeat loci chosen from the Genome Database. 方法無(wú)血緣關(guān)系樣本采自成都地區漢族群體。
- Brinkmann B,Klintschar M,Neuhuber F,et al.Mutation rate in human microsatellite:influence of the structure and length of the tandem repeat[J].Am J Hum.Genet,1998,62:1408. 庾蕾;伍新堯;李建金;等.;短串聯(lián)重復序列遺傳突變的觀(guān)察[M]
- It provides an experiment basis for combining highly genetic specificity of human euchromosome STR (Short Tandem Repeat, STR) with Y- chromosome STR study. 為結合具有高度遺傳特異性的人類(lèi)常染色體及Y染色體短串聯(lián)重復序列（Short Tandem Repeat, STR）的研究，構建墓葬血親關(guān)系深層次研究奠定了基礎。
- A method based on PCR was developed to amplify short tandem repeat(STR) in combination with denaturing gradient gel electrophoresis (DGGE) and silver dyeing. 應用聚合酶鏈反應擴增STR,經(jīng)變性凝膠電泳,再用銀染顯色方法,分析苯丙氨酸羥化酶(PAH)基因內含子3中TCTA重復序列的多態(tài)性。
- Allelotype analysis was done at five short tandem repeat markers (D17S855, D17S1322, D17S1323, D17S1326, and D17S1327) in or adjacent to BRCA1 on the recurrent mutation carriers. 對發(fā)現攜帶有相同突變的個(gè)體選取5個(gè)與BRCA1基因連鎖的標記（D17S855、D17S1322、D17S1323、D17S1326和D17S1327）進(jìn)行單倍型分析。
- Objective To investigate the alleles and genotype frequencies of 6 short tandem repeat (STR) loci DXS7130, DXS1214, DXS6799, DXS6804, DXS7424 and DXS7133 on the X chromosome in Chinese Han individuals living in Shaanxi province of Northwest China. 目的研究陜西西安漢族人群6個(gè)位于X染色體上的短串聯(lián)重復序列DXS7130、DXS1214、DXS6799、DXS6804、DXS7424和DXS7133等位基因及基因型頻率分布。
- Objective To investigate the alleles and genotypes frequency of 10 short tandem repeat (STR) loci (DXS101,DXS6789,DXS6799,DXS6804,DXS7130,DXS7132,DXS7133, DXS7423, HPRTB, DXS8378)on X chromosome of Chinese Hui nationality population. 目的研究寧夏回族群體X染色體上的10個(gè)短串聯(lián)重復序列(DXS101、DXS6789、DXS6799、DXS6804、DXS7130、DXS7132、DXS7133、DXS7423、HPRTB、DXS8378)的基因及基因型頻率分布。
- ObjectiveTo investigate the relationship between 48bp variant number tandem repeat (VNTR) polymorphism in the third exon of dopamine D 4 receptor(DRD 4) gene and attention deficit hyperactivity disorder (ADHD). 目的 探討多巴胺D4受體 (dopamineD4receptor,DRD4 )基因 48bp可變重復序列 (variantnumbertandemrepeat,VNTR)多態(tài)性與注意缺陷多動(dòng)障礙(Attention deficithyperactivitydisorder,ADHD)及其相關(guān)癥狀的關(guān)系。
- Materials and methods: Polymorphic analysis of MCC, DCC and YNZ22 loci that contain a variable number of tandem repeat(VNTR) was performed in 41 surgical specimens of colorectal carcinoma by the polymerase chain reaction(PCR). 方法：應用多聚酶鏈反應技術(shù)對41例大腸癌MCC、DCC基因和YNZ22位點(diǎn)的數量可變的重復序列（VNTR）區進(jìn)行了分析。
- Objective:To introduce the application of short tandem repeats in medicine. 目的：介紹短串聯(lián)重復序列在醫學(xué)中的應用。
- Methods: Polymorphic analysis of the genetic loci of YNZ22 and DCC containing a variable number of tandem repeat was performed in 46 surgically resected specimens of esophageal carcinoma with PCR. 方法：應用聚合酶鏈反應技術(shù)對46例食管癌YNZ22位點(diǎn)和DCC基因數目可變的串聯(lián)重復序列（VNTR）區進(jìn)行了分析。
- Aim:To set up a method of prenatal diagnosis of classic phenylketonuria ( PKU) by linkage analysis of the short tandem repeat(STR) in intron 3 linked to the phenylalanine hydroxylase (PAH) gene. 目的:建立一種利用苯丙氨酸羥化酶(PAH)基因內含子3中短串聯(lián)重復序列(STR)多態(tài)性連鎖分析進(jìn)行經(jīng)典型苯丙酮尿癥(PKU)產(chǎn)前診斷的方法。
- Microsatellites are short tandem repeats widely dispersed through out the eukaryotic genomes, consisting of tandem repeat sequences of 1 to 6 nucleotides. 微衛星(Microsatellite)是一種廣泛存在于真核生物基因組中的短的串聯(lián)重復序列，重復單位一般為1-6個(gè)核苷酸。
- Conclusions:Short tandem repeats are the major genetic markers used in medicine. 結論：短串聯(lián)重復序列是目前醫學(xué)中應用的主要遺傳標記。
- Results:Short tandem repeats were used widely for the study and clinic in medicine. 結果：短串聯(lián)重復序列已廣泛應用于醫學(xué)臨床和研究。
- Conclusion High level expression of epitope from HEV could be achieved by tandem repeats. 結論通過(guò)首位串聯(lián)可以實(shí)現HEV線(xiàn)性表位較高效的表達。
- Short tandem repeats (STRs) have been widely used in forensic sciences such as stain analysis and paternity testing. 摘要短串聯(lián)重復序列(STR)已被廣泛應用于法醫個(gè)體識別和親子鑑定中。
- Conclusion: The mutation of alleles often exists at the long, highly polymorphic tandem repeats in STRs. 結論:STR基因座的長(cháng)的、多態(tài)性高的串聯(lián)重復區是等位基因突變的敏感點(diǎn)。
