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- Genomic instability and mismatch repair mechanism 基因組不穩定性與錯配修復機制
- The study about mismatch repair has been analyzed thoroughly. 在核酸配對錯誤復上已有相當透澈的瞭解。
- Expression of mismatch repair gene hMSH2 in human adenocarcinoma of cervix and its clinical significance. 錯配修復基因hMSH2在宮頸腺癌組織中的表達
- But the large loop repair, a distinct repair from mismatch repair, is an unknown repair system. 但是大型核酸環(huán)的修復,一個(gè)迥異于配對錯誤的修復機制,卻是個(gè)未知的系統。
- Mismatch repair gene defects are recently identified in hematopoietic malignancies, leukemia and lymphoma cell lines. 錯配修復基因缺陷是最近在造血系統惡性腫瘤,白血病和淋巴瘤細胞株中被發(fā)現的。
- Conclusion A certain number of HNPCC families can be benefited from the genetic screening for mutation of the mismatch repair genes. 結論錯配修復基因的突變篩選可幫助、指導臨床對HNPCC家系進(jìn)行嚴密監控。
- A team at London's Hammersmith Hospital is attempting to reverse cirrhosis of the liver by harnessing and enhancing the body's own repair mechanism. 倫敦哈默史密斯醫院的一個(gè)小組嘗試以控制并提高身體自己的修補機制,來(lái)反轉肝的硬化。
- But if it isn’t, the DNA mismatch repair or MMR pathway targets damaged DNA bases and sets off the process of cell death via apoptosis. 但如果沒(méi)有修復的話(huà),DNA錯配修復途徑或MMR途徑會(huì )找到損傷的DNA堿基并且通過(guò)凋亡啟動(dòng)細胞死亡進(jìn)程。
- In recent years,deepgoing understanding of corneal endothelial cell wound about its pathology,healing process and repair mechanism has been achieved. 很多學(xué)者對角膜內皮愈合過(guò)程中各種因子的促進(jìn)作用進(jìn)行了系統的研究。
- The objective of this study was to define a multimarker prognostic model of 5-year survival in patients with lymph node-negative, mismatch repair (MMR)-proficient colorectal cancer (CRC). 這個(gè)研究的目的是探索淋巴結陰性的結直腸癌患者5年生存率的多標記預測模式。
- Modulation of O6-methylguanine-DNA methyltransferase(MGMT) and mismatch repair(MMR) expression in tumors and normal tissue is currently being investigated as a possible strategy ... 靶向DNA修復機制增強抗腫瘤化療藥物的療效、克服腫瘤耐藥正成為腫瘤個(gè)體化化療研究的一個(gè)重要領(lǐng)域。
- Un- derstanding the biological characteristics of gastric cancer has important meaning for the diagnoses, treatment and prognosis.hMSH2 and hMLH1 are belonging to mismatch repair (MMR) gene family. 因此,了解胃癌的生物學(xué)特性對于胃癌診斷、預后評估、指導治療有重要意義。
- This paper briefly introduces the repair mechanism of polymer alloy repair agent and concrete repairing technique. 本文簡(jiǎn)要介紹了高分子合金修補劑的修補機理及具體修補技術(shù)。
- Scientists would alter these cells by inserting genes or activating the cells'DNA - repair mechanisms. 科學(xué)家通過(guò)注入基因或激活細胞的脫氧糖核酸(DNA)修復機制來(lái)造基因。
- Objective To explore germline mutation frequencies and features of mismatch repaired gene MSH6 in persons with different kinds of colorectal cancer. 摘要目的了解錯配修復基因MSH6在不同形式大腸癌人群中的種系突變頻率及特征,提供真正的突變熱點(diǎn)。
- Be able to trouble shoot and repair mechanical, electrical and hydraulic systems. 能夠解決問(wèn)題、修理機械、電子及水力的系統。
- Scientists would alter these cells by inserting genes or activating the cells' DNA - repair mechanisms. 科學(xué)家通過(guò)注入基因或激活細胞的脫氧糖核酸(DNA)修復機制來(lái)造基因。
- Human DNA mismatch repair gene (hMMR) 錯配修復基因
- Since the human body has its own repair mechanisms, so when a serious loss of calcium, the body will involuntarily want to generate more bone cells. 由于人體有自行修復的機制,因此當鈣質(zhì)嚴重流失的時(shí)候,人體會(huì )不由自主地想要生成更多骨細胞。
- Mismatch repair is very important during replication to remove mismatches, or small insertion or deletion loops, that are generated by faulty replication. 在復制過(guò)程中,錯配修復對于去除由錯誤復制產(chǎn)生的錯配、插入環(huán)或缺失環(huán)是很重要的。