Mismatch repair gene defects are recently identified in hematopoietic malignancies, leukemia and lymphoma cell lines. 錯配修復基因缺陷是最近在造血系統惡性腫瘤，白血病和淋巴瘤細胞株中被發(fā)現的。
The genomic maintenance capability of MMR by both its repair and apoptotic functions underscores the importance of the MMR pathway in cancer biology and molecular medicine. 錯配修復系統通過(guò)它的修復和細胞凋亡功能維護基因組穩定性顯示了錯配修復途徑在癌癥生物學(xué)和分子醫學(xué)中的重要性。
