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- The majority of integrin signaling proceeds through focal adhesion kinase (FAK), an essential component of the focal adhesion complex. 大部分整合素的信號傳導是通過(guò)一種灶性附著(zhù)復合體的必需物質(zhì)--灶性粘附激酶實(shí)現的。
- An adhesion complex in the cell links to integrin that extends outward. 可見(jiàn)細胞連向整聯(lián)蛋白(8藍色)的粘連復合物。
- PURPOSE: To investigate the expression of focal adhesion kinase(FAK) and PTEN in salivary adenoid cystic carcinoma(SACC)and its significance. 摘要目的:探討黏著(zhù)斑激酶(FAK)和PTEN基因蛋白在腺樣囊性癌組織中的表達及意義。
- FAK (focal adhesion kinase) is a non-receptor tyrosine kinase that is widely expressed in vivo and highly conserved in structure. 粘著(zhù)斑激酶是一種在體內廣泛表達且結構高度穩定的非受體型酪氨酸激酶。
- Focal adhesion kinase (FAK) is the intermediator linking integrins to downstream signal proteins, and plays a key role in multiple signal pathways. 粘著(zhù)斑激酶(focal adhesion kinase,FAK)則是整合素信號途徑中連接整合素與下級信號分子的媒介,是胞內多條信號途徑的交匯點(diǎn)。
- To study the effect of antisense focal adhesion kinase (FAK) oligodeoxynucleotide on the biological behaviors of U251 MG cells. 目的探討反義黏著(zhù)斑激酶(FAK)對U251人膠質(zhì)瘤細胞株生物學(xué)行為影響。
- Objective The study investigated the effect of gastrin on tyrosine phosphorylation and protein expression of focal adhesion kinase (FAK) in human colon cancer cells. 目的研究胃泌素對人結腸癌細胞信號分子黏著(zhù)斑激酶(FAK)酪氨酸磷酸化和蛋白質(zhì)表達的影響。
- The expression and activity of the focal adhesion kinase on cultured Raji cells were regulated by Triptolide,and this regulation may be important in the tumor-pathogesis. 雷公藤內酯醇具有抗淋巴瘤細胞增殖效應,并同時(shí)降低FAK含量和活力,提示雷公藤內酯醇抗腫瘤效應可能與抑制黏著(zhù)斑激酶介導細胞信號轉導有關(guān)。
- Western blot analysis suggested the decreased cell motility might be attributed to the reduced phosphorylation of focal adhesion kinase (FAK) by PTEN gene delivery. 利用西方墨點(diǎn)法分析可以推測經(jīng)PTEN基因傳送的肝癌細胞移行數目的減少,可能是因降低了FAK磷酸化的緣故所致。
- FAK(focal adhesion kinase) discovered by Schaller is a major substance which can be activated by src-ingeneration protein-tyrosine kinase and it is a non-receptorprotein-tyrosion kinase. 黏著(zhù)斑激酶(focal adhesion kinase,FAK)是Schaller等發(fā)現的能被scr內源性蛋白酪氨酸激酶激活的主要底物,屬于非受體蛋白酪氨酸激酶,具有調節細胞發(fā)育、生長(cháng)、存活和凋亡,調節細胞與ECM(細胞外基質(zhì))黏附的功能。
- Focal adhesion kinase (FAK) is a critical mediator that connects integrin and the downstream signal molecules in integrin-signal transduction pathway, and is the convergence of many signal pathways. 黏著(zhù)斑激酶(focal adhesion kinase,FAK)是整合素信號轉導通路中連接整合素與下游信號分子的媒介,處于細胞內多條信號轉導通路的交匯點(diǎn),能激活多條信號轉導通路。
- The basic method is to use some micropatterns compounds, in activity of light occurs when focal adhesion or phacolytic of the left in the film the color film separations in the outlets. 其根基辦法是誑騙一些感平性化不合物涂料,在活性平照下爆發(fā)黏著(zhù)性或溶解性的改變,從而在片基上留住響應于不合色底片的不黑白網(wǎng)不面。
- These processes in turn depend on the dynamic control of both the actin cytoskeleton and focal adhesions. 這些過(guò)程反過(guò)來(lái)又依賴(lài)于對肌動(dòng)蛋白骨架和局部粘附的動(dòng)態(tài)控制。
- Previous core bx was reported as focal ADH. 以前粗針活檢報告為局灶性ADH。
- focal adhesion kinase gene (FAK) 局部黏著(zhù)斑激酶基因(FAK)
- Focal adhesion kinase related non -kinase 黏著(zhù)斑激酶相關(guān)非激酶
- focal adhesion targeting sequence 粘著(zhù)斑定位序列
- Mother and baby interact in a very complex way. 母親與嬰兒以非常復雜的方式相互影響。
- Dust the repair to prevent adhesion to outer cover. 清整修補處以防與外胎粘連。
- Some of them developed a great inferiority complex. 他們有些人養成了嚴重的自卑感。