FAK(focal adhesion kinase) discovered by Schaller is a major substance which can be activated by src-ingeneration protein-tyrosine kinase and it is a non-receptorprotein-tyrosion kinase.
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- 黏著(zhù)斑激酶(focal adhesion kinase,FAK)是Schaller等發(fā)現的能被scr內源性蛋白酪氨酸激酶激活的主要底物,屬于非受體蛋白酪氨酸激酶,具有調節細胞發(fā)育、生長(cháng)、存活和凋亡,調節細胞與ECM(細胞外基質(zhì))黏附的功能。