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- Most members of the XRCC genes family participated in several DNA repair pathways, including base excision repair, homologous recombination repair and non-homologous end joining. 目前已鑒定的這一基因家族的多數成員均參與幾種重要的DNA修復途徑,包括堿基切除修復、同源重組修復和非同源末端重接。
- BACKGROUND & OBJECTIVE: Adenosine diphosphate ribosyltransferase (ADPRT) and X-ray repair cross-complementing 1 (XRCC1) are 2major DNA base excision repair (BER) proteins and act interactively instimulating and executing BER processes. 背景與目的:DNA修復缺陷是腫瘤的遺傳易感因素。 二磷酸腺苷核糖轉移酶(adenosinediphosphateribosyltransferase,ADPRT)和X線(xiàn)修復交叉互補蛋白1(X-rayrepaircross-complementing1,XRCC1)是堿基切除修復的重要成分。
- Previous studies have shown that sustained ERK1/2 activation elicited by lead acetate (Pb(II)) enhances nucleotide excision repair synthesis and confers anti-cytotoxicity and anti-mutagenicity. 先前研究發(fā)現,醋酸鉛能藉由持續性活化之ERK1/2訊號而增加核苷酸切除修補能力及降低細胞毒性及基因突變。
- excision repair deficient mutant 剪切突變型
- Nucleotide Excision Repair and Human Disease 核苷酸切除修復和人類(lèi)疾病
- Excision repair cress-complementation group 1 核苷酸切除修復交叉互補組基因蛋白
- Excision repair cross-complementation group 1 切除修復交叉互補基因1
- Excision repair cross-completion 1 gene 切除修復交叉互補基因1
- Inhibitor of base excision repair 堿基切除修復抑制劑
- excision repair cross-complementing gene 1 (ERCC1) 切除修復交叉互補基因1
- excision repair cross-completion gene 1 修復交叉互補基因1
- Excision repair cross - complementing gene 1 ( ERCCI ) 切除修復交叉互補基因1
- excision repair cross complementing rodent repair deficiency 糾正鼠突變細胞切除修復缺陷
- She turned the chair on its side to repair it. 她把椅子翻轉過(guò)來(lái)修理。
- I have to wait in for the repair man. 我只得在家里等修理工。
- I'm all at sea; I've no idea how to repair cars. 我手足無(wú)措,不知道怎樣修理汽車(chē)。
- John managed to repair his car by himself. 約翰設法獨力修理自己的汽車(chē)。
- The lorry was damaged beyond hope of repair. 卡車(chē)嚴重損壞,已無(wú)修復的希望。
- Dust the repair to prevent adhesion to outer cover. 清整修補處以防與外胎粘連。
- I'm afraid this old radio is beyond repair. 恐怕這臺舊收音機不能修了。