BACKGROUND & OBJECTIVE: Adenosine diphosphate ribosyltransferase (ADPRT) and X-ray repair cross-complementing 1 (XRCC1) are 2major DNA base excision repair (BER) proteins and act interactively instimulating and executing BER processes.

 
  • 背景與目的:DNA修復缺陷是腫瘤的遺傳易感因素。 二磷酸腺苷核糖轉移酶(adenosinediphosphateribosyltransferase,ADPRT)和X線(xiàn)修復交叉互補蛋白1(X-rayrepaircross-complementing1,XRCC1)是堿基切除修復的重要成分。
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