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- Western blot analysis suggested the decreased cell motility might be attributed to the reduced phosphorylation of focal adhesion kinase (FAK) by PTEN gene delivery. 利用西方墨點(diǎn)法分析可以推測經(jīng)PTEN基因傳送的肝癌細胞移行數目的減少，可能是因降低了FAK磷酸化的緣故所致。
- Human Epithelial Cell Adhesion Molecul... 人上皮細胞粘附分子（Ep-CAM/CD362）試劑盒；
- PURPOSE: To investigate the expression of focal adhesion kinase(FAK) and PTEN in salivary adenoid cystic carcinoma(SACC)and its significance. 摘要目的：探討黏著(zhù)斑激酶(FAK)和PTEN基因蛋白在腺樣囊性癌組織中的表達及意義。
- FAK (focal adhesion kinase) is a non-receptor tyrosine kinase that is widely expressed in vivo and highly conserved in structure. 粘著(zhù)斑激酶是一種在體內廣泛表達且結構高度穩定的非受體型酪氨酸激酶。
- Focal adhesion kinase (FAK) is the intermediator linking integrins to downstream signal proteins, and plays a key role in multiple signal pathways. 粘著(zhù)斑激酶（focal adhesion kinase，FAK）則是整合素信號途徑中連接整合素與下級信號分子的媒介，是胞內多條信號途徑的交匯點(diǎn)。
- To study the effect of antisense focal adhesion kinase (FAK) oligodeoxynucleotide on the biological behaviors of U251 MG cells. 目的探討反義黏著(zhù)斑激酶(FAK)對U251人膠質(zhì)瘤細胞株生物學(xué)行為影響。
- The majority of integrin signaling proceeds through focal adhesion kinase (FAK), an essential component of the focal adhesion complex. 大部分整合素的信號傳導是通過(guò)一種灶性附著(zhù)復合體的必需物質(zhì)--灶性粘附激酶實(shí)現的。
- Another area of current interest concerns the possible role of cell surface glycoproteins in cell adhesion. 近來(lái)有興趣的另一領(lǐng)域是關(guān)于細胞表面糖蛋白在細胞的粘附中可能起的作用。
- Objective The study investigated the effect of gastrin on tyrosine phosphorylation and protein expression of focal adhesion kinase (FAK) in human colon cancer cells. 目的研究胃泌素對人結腸癌細胞信號分子黏著(zhù)斑激酶(FAK)酪氨酸磷酸化和蛋白質(zhì)表達的影響。
- The expression and activity of the focal adhesion kinase on cultured Raji cells were regulated by Triptolide,and this regulation may be important in the tumor-pathogesis. 雷公藤內酯醇具有抗淋巴瘤細胞增殖效應,并同時(shí)降低FAK含量和活力,提示雷公藤內酯醇抗腫瘤效應可能與抑制黏著(zhù)斑激酶介導細胞信號轉導有關(guān)。
- Cell adhesion activity of CEA on tumor cell lines was studied in the experiment. 本實(shí)驗對腫瘤細胞系的癌胚抗原(ea)胞粘附活性進(jìn)行了研究。
- These improvements further the applications of BFP in the field of cell adhesion. 這些拓展了生物膜力探針的應用范圍。 本文建立的方法學(xué)對于認識細胞粘附具有一定的意義。
- These molecules can promote cell adhesion and migration and are believed to play a role in tumor cell invasion. 細胞表面糖鏈通過(guò)與腫瘤細胞凝集素結合參與細胞間的作用。 因此，腫瘤細胞與基膜成份的粘著(zhù)，腫瘤細胞間、腫瘤細胞與宿主細胞的粘合是癌轉移過(guò)程中的重要步驟。
- E-cadherin, as a cell adhesion molecule containing high mannose type N-linked glycan, mediates homotypic cell adhesion. E-鈣粘蛋白作為含有高甘露糖型N-糖鏈的細胞粘附分子，介導著(zhù)細胞間的嗜同性粘附。
- Cell adhesion forces were measured by means of micropipette aspiration technique. 細胞粘附力采用微管吸吮技術(shù)進(jìn)行測定。
- Cell adhesion has a vital effect on renal inflammatory injury, renal tubular lesions and interstitial fibrosis. 其在腎臟炎性病變、腎小管損傷、腎間質(zhì)纖維化等發(fā)生發(fā)展中起重要作用。
- FAK(focal adhesion kinase) discovered by Schaller is a major substance which can be activated by src-ingeneration protein-tyrosine kinase and it is a non-receptorprotein-tyrosion kinase. 黏著(zhù)斑激酶(focal adhesion kinase，FAK)是Schaller等發(fā)現的能被scr內源性蛋白酪氨酸激酶激活的主要底物，屬于非受體蛋白酪氨酸激酶，具有調節細胞發(fā)育、生長(cháng)、存活和凋亡，調節細胞與ECM(細胞外基質(zhì))黏附的功能。
- The factors which destroy this complex will breakdown the homotypic cell adhesion. 任何破壞細胞內該復合體的因素也將使細胞黏附功能喪失。
- Focal adhesion kinase (FAK) is a critical mediator that connects integrin and the downstream signal molecules in integrin-signal transduction pathway, and is the convergence of many signal pathways. 黏著(zhù)斑激酶(focal adhesion kinase，FAK)是整合素信號轉導通路中連接整合素與下游信號分子的媒介，處于細胞內多條信號轉導通路的交匯點(diǎn)，能激活多條信號轉導通路。
- In the early stage of cell adhesion, as the contractility of actin cytoskeleton reduced, Rho would be activated.2. 細胞形態(tài)和微絲骨架（應力纖維）排布的調整；細胞的增殖與遷移等。
