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- Objective:To observe the expression of amyloid precursor protein(APP)in the hippocampi of senescence accelerated mice prone 8(SAMP8). 目的:觀(guān)察淀粉樣前體蛋白(APP)在快速老化癡呆小鼠P8(SAMP8)海馬中的表達,探討其與SAMP8小鼠增齡性變化的關(guān)系。
- Objective To prepare transgenic mice model of human (Swedish mutation of amyloid precursor protein, APP SWE ) gene. Methods By pronuclear microinjection, human APP SWE genes were microinjected into pronuclei of zygotes of C57 and Kunming white mice. 目的 建立攜帶人類(lèi)淀粉樣前體蛋白瑞典型突變 (Swedish mutation of amyloid precursorprotein,APPSWE)基因的轉基因小鼠模型。
- They alter the way it cleaves amyloid precursor protein. 它們改變了這個(gè)酶切割淀粉樣蛋白前體的方式。
- Those engineered to overproduce a mutant form of the human amyloid precursor protein, for instance, have fewer than normal neurons in the hippocampus. 例如，被改造成會(huì )產(chǎn)生過(guò)量突變形式的類(lèi)淀粉前驅蛋白（amyloidprecursorprotein）的小鼠，其海馬神經(jīng)元數目會(huì )比正常小鼠來(lái)得少。
- Keywords Alzheimer disease（AD）;amyloid precursor protein APP;calcium homeostasis;cytochrome oxidase（CO）;deleterious network;heart benefiting recipe（HBR）; 阿爾茨海默病;細胞色素氧化酶;淀粉樣前體蛋白;鈣穩態(tài);有害網(wǎng)絡(luò );調心方;
- secretase of amyloid precursor protein 淀粉樣前體蛋白分泌酶
- Amyloid precursor protein (APP) 淀粉樣前體蛋白
- amyloid precursor protein(APP) 淀粉樣前體蛋白
- Effect of selegiline on amyloid precursor protein processing 烷丙苯胺對淀粉樣前體蛋白代謝的影響
- α secretase form of soluble amyloid precursor protein (sAPPer) 可溶性淀粉樣前體蛋白α
- Silencing effect of amyloid precursor protein triggered by small interfering RNA 小干擾RNA對人淀粉樣前體蛋白基因的沉默作用
- The Construction of a Screening System of Human Amyloid Precursor Protein and Enhanced Fluorescence Protein Fusion Gene 人淀粉樣前體蛋白基因與綠色熒光蛋白融合基因篩選系統的建立
- Advances in Molecular Biology and Clinical Study of Amyloid Precursor Protein for Alzheimer's Disease 淀粉樣前體蛋白在阿爾茨海默病分子生物學(xué)和臨床醫學(xué)中的研究進(jìn)展
- GABA inhibits release of soluble amyloid precursor protein from rat hippocampal brain slices 氨基丁酸抑制大鼠海馬腦片可溶性淀粉樣前體蛋白的釋放
- Effect of Swedish mutation of amyloid precursor protein gene on cerebral ischemia induced by photothrombosis 淀粉前體蛋白基因的Swedish突變對光化學(xué)法所致腦缺血的影響
- Keywords amyloid precursor protein;C terminal fragment;premarin;progynova;hippocampus;cortex; 淀粉樣蛋白前體;羧基端片段;倍美力;補加樂(lè );海馬;腦皮質(zhì);
- Keywords cyclosporin A;calcineurin;amyloid precursor protein;stretch injury;neurocytes; 環(huán)孢霉素A;鈣調神經(jīng)磷酸酶;淀粉樣前體蛋白;牽張損傷;神經(jīng)細胞;
- Keywords Alzheimer s disease;amyloid precursor protein;presenilin;apolipoprotein E;gene; 阿爾茨海默病;淀粉樣前體蛋白;早老素;載脂蛋白E;基因;
- Keywords Alzheimer's disease;plasma;amyloid precursor protein;tubulin;diagnosis; 阿爾茨海默病;血漿;淀粉樣蛋白前體;微管蛋白;診斷;
- Establishment of a cell model of overexpression of amyloid precursor protein and its effect on the proliferation and apoptosis of cells 淀粉樣前體蛋白過(guò)度表達細胞模型的建立及對細胞增殖和凋亡的影響
