Objective To prepare transgenic mice model of human (Swedish mutation of amyloid precursor protein, APP SWE ) gene. Methods By pronuclear microinjection, human APP SWE genes were microinjected into pronuclei of zygotes of C57 and Kunming white mice.

 
  • 目的 建立攜帶人類(lèi)淀粉樣前體蛋白瑞典型突變 (Swedish mutation of amyloid precursorprotein,APPSWE)基因的轉基因小鼠模型。
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