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- TH陽(yáng)性神經(jīng)元TH-ir neuron
- 免疫組化檢測,成功模型光鏡下分別計數雙側黑質(zhì)TH陽(yáng)性神經(jīng)元,損毀側黑質(zhì)TH陽(yáng)性神經(jīng)元占正常側的3.8%,即毀損側TH陽(yáng)性神經(jīng)元減少96.2%。The immunohistochemical staining showed a significant reduction(in 3.8%25)of TH-positive neurons in the 6-OHDA injection side compared with the opposite side.
- 此外,我們還發(fā)現一種特異性興奮PI-linked多巴胺受體的化合物SKF83959,激活PLC-IP_3-Ca~(2+)下游信號轉導通路,引起胞內Ca~(2+)濃度明顯上升,促進(jìn)FGF-2蛋白合成和分泌,有效地保護TH陽(yáng)性神經(jīng)元的存活。APO failed toinduce FGF-2 upregulation in astrocytes transfected with pEGFP-RGS2.In this study we characterized SKF83959, a selective agonist for the PI-linkedD1 liked DAR, stimulated IP3 hydrolysis and increased intracellular Ca2+. Via thismolecular mechanism, SKF83959 induced FGF-2 biosynthesis and secretion inastrocytes, thereby promoting survival of TH positive neurons.
- 在頸上神經(jīng)節內發(fā)現了TH陽(yáng)性細胞,細胞體為圓形或卵圓形。 TH免疫反應亦見(jiàn)于小強熒光細胞(SIF cells)。TH-positive cells are observed in the SCG and the cell bodies are round or oval, TH-positive cells are also observed in SIF cells(small intensely fluorescent cells).
- 無(wú)論是實(shí)驗組還是對照組,L3-L5 DRG中SP陽(yáng)性神經(jīng)元的比例均高于L1和L2中的比例。And the ratio of SP-ir neurons in L1 and L2 DRGs was significantly lower than those in L3-5 DRGs (P<0.001).
- 與PBS對照側相比,LPS注入黑質(zhì)導致TH陽(yáng)性細胞數下降至38%; SB203580預處理可以顯著(zhù)增加TH+細胞數達63%(P<0.05)。Compared with PBS control side , TH-positive neurons inthe SNdecreased by 68%25, TH-positive neurons in the SN preconditioned by specific inhibitor SB203580 increased significantly .
- 辣椒素對大鼠三叉神經(jīng)節一氧化氮合酶陽(yáng)性神經(jīng)元的影響Effect of capsaicin on nitric oxide synthase positive neurons in trigeminal ganglion of rats
- 汞中毒對大鼠學(xué)習記憶能力和海馬NADPH-d陽(yáng)性神經(jīng)元的影響The research on Learning Memory and NADPH-d Positive Neurons in Hippocampus of Chronic Mercury-exposed Rats
- 6-OHDA注射24天后,大鼠黑質(zhì)TH陽(yáng)性細胞大部分消失,但在腹腔注射BBA后,黑質(zhì)TH陽(yáng)性細胞存活明顯增多,其中10 mg·kg~(-1)·d~(-1)的BBA的作用最強(P<0.01);In 6-OHDA-lesioned SN, most TH-positive neurons disappeared, while in BBA-treated rats there were more survival neurous observed. The neuroprotective action of BBA was most potent at the dose of 10 mg. kg~(-1).
- 陽(yáng)性神經(jīng)元positive neurons
- NOS陽(yáng)性神經(jīng)元NOS positive neurons
- 免疫陽(yáng)性神經(jīng)元immunopositive neuron
- AChE陽(yáng)性神經(jīng)元AChE positive neurons
- ChAT陽(yáng)性神經(jīng)元ChAT-positive neurons
- Fos免疫陽(yáng)性神經(jīng)元Fos-like immunoreactive neuron
- 大鼠尾殼核頭部一氧化氮合酶陽(yáng)性神經(jīng)元區域性分布和腦缺血后變化THE DISTRIBUTION AND ISCHEMIA-INDUCED CHANGES OF NITRIC OXIDE SYNTHASE POSITIVE NEURONS IN THE HEAD OF NUCLEUS CAUDATUS PUTAMEN IN RATS
- 局部皮質(zhì)內注射海仁酸對皮質(zhì)和海馬一氧化氮合酶陽(yáng)性神經(jīng)元的影響。Local injection of kainic acid causes widespread degeneration of NADPH-d neurons and induction of NADPH-d in neurons, endothelial cells and reactive astrocytes.
- 一氧化氮合酶陽(yáng)性神經(jīng)元NOS-positive neuron
- NGF誘導大鼠胚腦皮層和隔區神經(jīng)干細胞向神經(jīng)元和AChE陽(yáng)性神經(jīng)元分化的作用Effects of NGF on inducing the rat embryonic neural stem cells derived from cortex and septal region to differentiate into neurons and AChE positive neurons in vitro
- 促腎上腺皮質(zhì)激素及電針對甲醛痛敏大鼠脊髓一氧化氮合成酶陽(yáng)性神經(jīng)元的影響Effects of adrenocorticotropic hormone and electroacupuncture on formalin- induced NOS-positive neurons in the spinal cord of rats
