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- Objective To evaluate the efficacy and safety of pulmonary surfactant(PS)in the replacement therapy for neonatal respiratory distress syndrome(NRDS). 目的評價(jià)肺表面活性物質(zhì)(PS)替代治療新生兒呼吸窘迫綜合癥(NRDS)的療效及安全性。
- Objective The aim of this study was to determine the therapeutic effect of pulmonary surfactant (PS) on the development of bronchopulmonary dysplasia (BPD) in premature infants. 目的探討肺表面活性物質(zhì)(PS)對支氣管肺發(fā)育不良(BPD)的預防和治療意義。
- AIM To investigate the ruthenium red (RR) staining on the visualizing of ultrastructures of pulmonary surfactant (PS) in injured lungs caused by bleomycin (BLM). 目的 觀(guān)察釕紅染色方法對博萊霉素 (BL M)肺損傷早期肺表面活性物質(zhì) (PS)的超微結構的效果 .
- Previous study showed that ALI/ARDS patients had abnormal pulmonary surfactant(PS)system. PS inducer therapy could ease ALI/ARDS and retain pulmonary function. 有研究表明,ALI/ARDS患者存在內源性肺表面活性物質(zhì)(PS)系統異常,內源性PS誘導劑治療對減輕ALI/ ARDS病情、促進(jìn)肺功能恢復有顯著(zhù)作用,但在百草枯中毒導致的ALI/ARDS中的作用未見(jiàn)報道。
- AIM: To study the change of pulmonary surfactant (PS), lipid peroxide (LPO), and the protective effects of astragalius membranaceus on the ischemia-reperfusion (I/R) injury. 摘要目的:探討腸缺血-再灌注損傷時(shí),肺表面活性物質(zhì)及脂質(zhì)過(guò)氧化物(LPO)含量的改變及其意義,以及黃芪在缺血-再灌注過(guò)程中對肺損傷的保護作用。
- To research the change of plasma fibronectin (Fn) and pulmonary surfactant (PS) and the effect of 654 2 on the content of Fn and PS in rabbits with pulmonary edema caused by oleic acid. 目的:實(shí)驗觀(guān)察油酸型急性肺水腫家兔血漿纖維連接蛋白(Fn)和肺表面活性物質(zhì)(PS)含量的變化,以及給予山莨菪堿(654-2)后對其變化的影響。
- Pulmonary surfactants(PS) is important to maintain the normal lung function,and surfactant alterations have been implicated in the pathophysiology of acute respiratory distress syndrome(ARDS). 肺表面活性物質(zhì)(PS)在維持正常的肺功能起著(zhù)重要作用,業(yè)已證明,PS異常與急性呼吸窘迫綜合征(ARDS)的發(fā)病有關(guān)。
- Pulmonary surfactant therapy in premature infants with respiratory distress syndrome. 肺表面活性物質(zhì)治療早產(chǎn)兒呼吸窘迫綜合征。
- Effect of four mechanical ventilation modes on pulmonary surfactant in early stage after severe smoke inhalation injury in dogs. 機械通氣對嚴重煙霧吸入傷犬早期肺表面活性物質(zhì)的影響。
- His professional interests include the study of regulation of pulmonary surfactant synthesis, the function of Clara cells, and the molecular mechanisms of acute lung injury. 細胞抗肺纖維化及外周谷氨酸受體過(guò)度激活在急性肺損傷發(fā)生中作用的研究。
- Objective Pulmonary surfactant protein-D(SP-D) is regarded as a valuable biomarker in acute lung injury(ALI) and acute respiratory distress syndrome(ARDS). 目的肺表面活性物質(zhì)蛋白D(SP-D)被認為是急性肺損傷(ALI)和急性呼吸窘迫綜合征(ARDS)有價(jià)值的生物指標。
- Among those, DPPC (Dipalmitoyl Phosphatidylcholine) is the major component which contributes to the surface tension lowering ability of pulmonary surfactant. 在這些成份當中又以DPPC為主要的成份,而DPPC經(jīng)過(guò)證實(shí)是降低肺泡界面表面張力的主要成份。
- OBJECTIVE To develop a headspace capillary gas chromatography method for the determination of residual organic solvents in porcine pulmonary surfactant. 目的建立頂空毛細管氣相色譜法測定豬肺表面活性物質(zhì)中的有機溶劑殘留量。
- OBJECTIVE To develop a HPLC-ELSD method for the determination of seven phospholipid components in porcine pulmonary surfactant and its lyophilized powder. 目的建立豬肺表面活性物質(zhì)及其凍干粉中7種磷脂組分的含量測定方法。
- Newborn may get respiratory distress syndrome even to death for deficiency of pulmonary surfactant and formation of pulmonary atelectasis and hyaluronic membrane in alveoli. 初生兒也可因缺乏肺表面活性物質(zhì);發(fā)生肺不張和肺泡內表面透明質(zhì)膜形成;造成呼吸窘迫綜合征;導致死亡.
- The pathogenesy of smoke inhalation acute lung injury/acute respiratory distress syndrome(ALI/ARDS) is not completely clear,perhaps concerned with oxidative damage,the change of pulmonary surfactant and cytokine,and apoptosis. 目前煙霧吸入性急性肺損傷(ALI)/急性呼吸窘迫綜合征(ARDS)的發(fā)病機制尚未完全明確,可能與煙霧所致的氧化性損傷、肺表面活性物質(zhì)變化、細胞因子改變、細胞凋亡的發(fā)生有關(guān)。
- Lining at the air-liquid interface, pulmonary surfactant is a complex mixture of 90% lipids and 10% proteins. The major phospholipid (75%) is dipalmitoylphosphatidylcholine (DPPC) . 位于肺的液氣交界面的肺泡表面活性物質(zhì)由大約90%25的脂質(zhì)和10%25的蛋白質(zhì)組成,脂質(zhì)中90%25為磷脂,主要(75%25)是二棕櫚酰磷脂酰膽堿(dipalmitoylphosphatidylcholine,DPPC)使得肺泡呼氣末表面張力較小。
- Keywords Pulmonary surfactant (PS);Premature;Neonatal respiratory distress syndrome(NRDS); 肺表面活性物質(zhì)(PS);早產(chǎn)兒;新生兒呼吸窘迫綜合征(NRDS);
- pulmonary surfactant protein A like molecules 肺表面活化蛋白A相似分子
- pulmonary surfactant replacement 肺表面活性劑替代物