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- K562/A02細胞株K562/A02 cell line
- 目的:初步研究逆轉劑漢防己甲素(Tet)和屈洛昔芬(DRL)對K 562/A02細胞株凋亡相關(guān)因子bcr/abl mRNA及蛋白表達的影響。Objective To observe the effect of Tetrandrine in combination with Droloxifen on the expression of bcr/abl mRNA and P~(210) BCR/ABL protein of K562/A02 cell line.
- K562/A02細胞K562/A02 cell
- 細胞cell
- K562/A02人白血病細胞株Human leukemia cell line K562/A02
- K562/A02細胞K562/A02 cell
- 細胞株cell strain
- 漢防己甲素聯(lián)合屈洛昔芬對K562/A02細胞bcr/abl表達的影響Effect of Tetrandrine in Combination With Droloxifen on the Expression of bcr/abl mRNA and Protein of K562/A02
- 人淋巴因子激活的殺傷細胞對肝癌細胞株凋謝作用的觀(guān)察A Observaion of Apoptoisi of Liver Cancer Cells Induced by Human LAK Cells
- Tet、DRL和DNR單獨應用對K562/A02細胞bcr/ablmRNA及蛋白表達均無(wú)影響;The application of single drug of Tet or DRL has no effect on bcr/abl mRNA and BCR/ABL protein expression in K562/A02 cell line.
- T24細胞株T24 Cell lines
- Tet和DRL聯(lián)合應用于48h開(kāi)始下調K562/A02細胞bcr/abl mRNA表達,于72h開(kāi)始下調K562/A02細胞P~(210) BCR/ABL蛋白表達;However,Tet in combination with DRL begins to downregulate bcr/abl mRNA and P~(210) BCR/ABL expression of K562/A02 cells at 48h and 72h respectively.
- NB4細胞株NB4 cell line
- 肝細胞株hepatocyte lines
- FCM檢測K562細胞、雷洛昔芬(2.5mg/L)及CsA( 1mg/L)單獨及聯(lián)合作用于K562/A02細胞一定時(shí)間細胞內DNR濃度。Pretreating K562/A02 cells with raloxifene(2.5mg/L)or CsA( 1mg/L) for 48 hours partially restored the sensitivity of K562/A02 cells to DNR (IC50 were5.98mg/L and 8.15mg/L respectively) but had no effect on K562 cells;
- A20細胞株A20 cell line
- B9細胞株B9 cell line
- 采用流式細胞儀(FCM)檢測K562細胞、雷洛昔芬(2.5mg/L)及CsA( 1mg/L)單獨及聯(lián)合作用于K562/A02細胞一定時(shí)間細胞膜上P-gp的表達。and p-glycoprotein expression was detected by fluorometry . Results: The IC50 of DNR for K562/A02 and K562 cells were 23.51mg/L and0.29mg/L respectively.
- CEM細胞株CEM cell line
- CHO細胞株CHO cell