您要查找的是不是:
- Bip抗體immunoglobulin binding protein (Bip) antibody
- 人GRP78基因human's GRP78 gene
- GRP78/BipGRP78/Bip
- 內質(zhì)網(wǎng)分子伴侶GRP78endoplasmic reticulum molecular chaperon GRP78
- 二進(jìn)制整數程序設計(BIP)Binary Integer Programming (BIP)
- 長(cháng)時(shí)間腦缺血后導致內質(zhì)網(wǎng)功能下降,GRP78、GRP94表達下降。Endoplasmic reticulum(ER) dysfunction is occurred after the long time cerebral ischemia and the expressions of GRP are down-regulated.
- 如果要求 EDC的檢測效率至少不低于 90% ,可以采用 2× BIP- 4差錯檢測方案 ;2*BIP 4 EDC should be adopted to meet the requirement that the detection efficiency be no less than 90%25;
- 細胞對這種應激的反應是增加一系列內質(zhì)網(wǎng)分子伴侶如GRP94、GRP78和PDI等的表達。Normal cells respond to ER stress by increasing transcription of genes encoding ER-resident molecular chaperones such as GRP94, GRP78 and PDI to facilitate protein folding.
- 真核細胞內質(zhì)網(wǎng)中未折疊蛋白的積累會(huì )引起內質(zhì)網(wǎng)脅迫(ER stress),激活未折疊蛋白應答(UPR)信號途徑,從而誘導內質(zhì)網(wǎng)中分子伴侶的表達(比如BiP和Calnexin等)。The accumulation of unfolded proteins in the endoplasmic reticulum (ER) lumen causes ER stress response, activates the unfolded protein response (UPR) signal pathway and consequently induces the expression of ER-located molecular chaperones (such as BiP, calnexin, etc.) in eukaryote cells.
- 葡萄糖調節蛋白(glucose regulated proteins, GRPs)是內質(zhì)網(wǎng)中一類(lèi)重要的駐留蛋白,包括GRP78和GRP94。 GRP94是熱休克蛋白HSP90家族的成員之一,與HSP90具有50%的同源性,是高度保守的蛋白。Ilie glucose - regulated proteins ( GRPs) are important resident proteins of the ERs, including GRF78 and GRP94. GRP94 is a member of the heat shock protein90 ( HSP90) family.