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- FLT3/ITD突變Flt-3/ITD mutation
- 方法采用基因組PCR及RT-PCR方法檢測126例AML患者的FLT3/ITD突變。Methods Reverse transcription polymerase chain reaction (RT-PCR) and genomic PCR were applied to monitor FLT3/ITD mutation in 126 AML patients.
- 伴有染色體易位且FLT3/ITD突變的急性髓性白血病患者預后較差,染色體易位和FLT3/ITD突變可以作為其預后不良的重要標志。The prognosis is relatively poor in FLT3/ITD mutation patients with chromosome translocation. FLT3/ITD mutation with chromosome translocation may be an important marker for poor prognosis of AML.
- Flt-3／ITD突變Flt-3/ITD mutation
- FLT3/ITD陽(yáng)性AML患者早期死亡率高,FLT3/ITD陽(yáng)性M3患者預后差,FLT3/ITD突變檢測對于A(yíng)ML患者療效評價(jià)、預后估計具有重要意義。FLT3/ITD was associated with a higher early case fatality rate in AML patients and a poor prognostic in APL patients. The detection of FLT3/ITD mutation will be valuable in therapeutic efficacy evaluation and prognostic assessment in AML patients.
- FLT3-ITDFLT3-ITD
- Flt3配體Flt3 ligand
- FLT3基因FLT3 gene
- ITD模態(tài)識別ITD modal identification
- FLT3內部串聯(lián)復制FLT internal tandem duplication
- 油底殼模態(tài)參數識別ITD法The Identification of Modal Parameters of the Oil pan with ITD Algorithm
- 突變表型mutant phenotype
- 天氣突變。There was a sudden change in the weather.
- 腺病毒介導的Flt3配體小鼠肝癌治療研究Flt3 Ligand gene therapy of murine liver cancer mediated by recombinant adenovirus vector
- 在M3患者中,FLT3/ITD陽(yáng)性者完全緩解率低(P=0.015)。The CR rate was lower in acute promyelocytic leukemia (APL) patients with FLT3/ITD (P=0.015).
- ｔｓ突變體temperature-sensitive mutant
- DIG摻入PCR半定量檢測AML中Flt3基因的表達THE EXPRESSION OF FLT3 GENE IN AML DETECTED BY SEMI-QUANTITATIVE RT-PCR WITH INCORPORATION OF DIG
- 珠江水系廣州河段水體中有機污染物的GC/ITD/COM聯(lián)用法分析GC/ITD/COM Combined Analysis of Organic Pollutants in Guangzhou Urban Section of Pearl River Water System
- 半致死突變semilethal mutation
- THP-1、HL-60是FLT3野生型過(guò)表達的AML細胞株。THP-1 and HL-60 are AML cell lines with wild-type FLT3 receptor but over-express it in mRNA and protein levels.
