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- Methods Nick translation assay was used to detect the level of DNA strand break. 方法 用缺口翻譯技術(shù)檢測DNA鏈斷裂 ,用軟瓊脂克隆形成率評價(jià)細胞轉化。
- CAT and PARP participated in the induction of peroxidative adaptation to DNA strand break. CAT和PARP參與過(guò)氧化DNA斷裂的適應誘導。
- There were peroxidative adaptive responses to non lethal damage of high concentration H 2O 2 in both cellular viability and DNA strand break levels; but adaptive models (conditions) between the two levels were different. 在細胞活力和DNA斷裂水平上均觀(guān)察到非致死性適應反應，然而這兩種水平的適應模式（條件）有所不同，提示兩者可能存在不同的誘導適應的途徑。
- Conclusion Organic extracts of CDW from three raw water sources of C river, H river and D lake in Wuhan could induce DNA strand breaks in HepG2 cells. 最高濃度氯化飲水有機提取物誘導 Hep G2 DNA損傷的強度 ;H水 >D湖和 C江 (均 P<0 .;0 1)。
- Furthermore, measuring irradiationinduced DNA strand breaks with this modified method, G(SSB) and G(DSB) consisted with other researches were obtained. 以此改進(jìn)方法檢測電離輻射誘導的DNA單、雙鏈斷裂，可得到與其它研究結果相一致的G(SSB)和G(DSB)值。
- Apoptosis of immature thymocyte of mice induced by dexamethason and DNA strand broken cells induced by K 2Cr 2O 7 were tested by comet assay. 應用彗星試驗對地塞米松誘導的小鼠胸腺凋亡細胞與重鉻酸鉀誘導的普通DNA鏈斷裂損傷細胞進(jìn)行了比較研究。
- Methods After mice were fed with taurine or Vit C or Vit E respectively for 112 days, DNA strand breaks could be detected by fluorometric assay of DNA unwinding(FADU) and were compared with the control group. 方法小鼠飼料中分別添加?；撬?、維生素C（VitC）和維生素E（VitE）喂養112d后，熒光法（FADU法）檢測小鼠脾細胞DNA鏈的斷裂程度，并與對照組比較。
- Study of the Effects of Copper Sulphate on Splenocyte DNA Strand Breaks in Mice 硫酸銅對小鼠脾細胞DNA損傷研究
- The effects of Formaldehyde were both a DNA strands breaks and DNA-Protein crosslink, and the latter can work severe genotoxicity on cells, that could be the molecule mechanism of leukemia cause by formaldehyde. 甲醛可造成骨髓細胞DNA的斷裂和DNA-蛋白質(zhì)交聯(lián),而DNA-蛋白質(zhì)交聯(lián)可以對細胞產(chǎn)生嚴重的遺傳毒性,這可能是甲醛導致白血病的分子機制。
- Keywords sodium pentachlorophen;immunocyte;DNA strand breaks;micronuclei; 五氯酚鈉;免疫細胞;DNA鏈斷裂;微核;
- In situ detection of DNA strand breaks in rat brain after transient focal ischemia 大鼠局灶性腦缺血再灌注DNA損傷原位檢測
- Genes are arranged in order along the DNA strand within the chromosome. 存在于染色體內的DNA長(cháng)鏈上的基因呈有序排列。
- The NBS1 is a component of the MRE11/RAD50/NBS1 complex (MRN) and plays a critical role in the DNA double strand break (DSB) repair and the maintenance of chromosomal integrity. NBS1作為MRE11/RAD50/NBS1復合物的組分之一,是細胞應答DNA損傷的一個(gè)關(guān)鍵蛋白質(zhì),在DNA雙鏈斷裂修復和維持基因組穩定中發(fā)揮重要的作用。
- Effect of 1,10-phenanthroline on DNA strand breaks induced by different oxidants and doxorubicin in CHL cells 菲???圓煌?躉?梁投噯岜刃撬??HL細胞DNA鏈斷裂的影響
- Study on DNA Strand Breaks and Mutation Spectrum Induced by Low-energy Heavy Ions 低能重離子引起DNA鏈斷裂和誘發(fā)基因突變譜的研究
- Keywords Peroxynitrite;8-Hydroxydeoxyguanosine;DNA strand breaks;Flavonoids;Inhibitors; 過(guò)亞硝酸根;8-羥基脫氧鳥(niǎo)苷;DNA鏈斷裂;黃酮類(lèi)化合物;抑制劑;
- 2)EFP induced apoptosis of MVEC,and the degree of apoptosis of the cells and the level of DNA strand breaks were dependent on the EFP concentration. 2)EFP可誘導MVEC細胞凋亡,且成劑量依賴(lài)關(guān)系,用單細胞凝膠電泳法檢測細胞凋亡,隨著(zhù)EFP濃度的增大,拖尾細胞增多;
- The separate or combined effect of cigarette smoking and chrysotile on DNA strand breaks in human embryo lung cells 王起恩,樊晶光,張俠, 急性重型減壓病并腸穿孔1例聶翠艷,滕燕生,孫長(cháng)豐,張勤,王曙光
- Radiosensitization effect of 3-aminobenzamide( 3-AB), a specific inhibitor of ADP-ribose transferase( ADPRT), on cell colony formation and DNA double strand break (DSB), repair of human tumor cells was studied. 目的：從細胞的克隆形成能力和細胞DNA雙鏈斷裂及修復幾方面探討了ADP－核糖基轉移酶（ADPRT）的特異性抑制劑3－氨基苯甲酰胺（3－AB）對人卵巢癌細胞株HOC8的放射增敏效應。 結果表明，3－AB能降低受照細胞的克隆形成能力；
- Using plasmid pGEM-3Zf(-) and M13mpl8 RF DNA, this thesis studied the DNA damage (DNA single strand break (SSB) and double strand break (DSB)), and gene mutation spectra induced by 30keV N+, C+ ions. 本文以質(zhì)粒、噬菌體為實(shí)驗材料，主要研究30keV的N~+、C~+引起的DNA分子損傷(單雙鏈斷裂)和它誘發(fā)基因突變的特點(diǎn)和規律。
