The effects of Formaldehyde were both a DNA strands breaks and DNA-Protein crosslink, and the latter can work severe genotoxicity on cells, that could be the molecule mechanism of leukemia cause by formaldehyde.
英
美
- 甲醛可造成骨髓細胞DNA的斷裂和DNA-蛋白質(zhì)交聯(lián),而DNA-蛋白質(zhì)交聯(lián)可以對細胞產(chǎn)生嚴重的遺傳毒性,這可能是甲醛導致白血病的分子機制。