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- CD40LCD40 ligand
- CD40-CD40LCD40-CD40L
- CD154Anti-CD154
- 可溶性CD40LsCD40L
- 可溶性CD154sCD 154
- CD40L在川崎病發(fā)病機制中的作用探討The roles of CD40 ligand in the pathogenesis of Kawasaki disease
- CD154／CD40LCD154/CD40L
- CD154單克隆抗體CD154 mAb
- CD28與CD40／CD154co-stimulatory molecules
- CD40L異常表達及血清中E-選擇素在川崎病發(fā)病機制中起重要作用。CD40L and E-selection might play a role in the immunopathogenesis of KD.
- 共刺激分子CD40/CD40L和OX40/OX40L在乳腺癌中的表達及其生物學(xué)意義The Expression of Co-stimulators CD40/CD40L and OX40/OX40L and Their Biological Roles in Human Breast Cancer
- D組聯(lián)合應用CD4+ CD25+ T細胞和CD154單抗。group D, CD4+ CD25+ Treg in combination with anti-CD154 was given.
- 川崎病患兒CD4+T細胞表面CD40L表達與E-選擇素水平正相關(guān)(r=0.626,P<0.05)。There was a significantly positive correlation between CD40L expression on CD4+T-cells in patients with KD and E-selection(r=0.626, P<0.05).
- 采用國內外公認的對人具有明顯免疫增強作用的CpG2006，通過(guò)分子偶聯(lián)技術(shù)合成CpG2006復合物(CD40L-pLL-CpG2006)。Applied FACS to assess the uptake rate of CpG2006 and to analysis the expression level of CD 19, CD20, CD22 and CDS.
- 與正常人對照相比,SLE外周血B淋巴細胞中CD154誘導NF-資B核轉移存在顯著(zhù)異常,類(lèi)似生發(fā)中心表型。CD154-induced NF-kB nuclear translocation is abnormal in human lupus B lymphocytes with phenotype analogous to germinal center B cells.
- CD3+T細胞上CD154表達的PPC,刺激前健康老年組高于健康青年組(P<0.05),低于老年肺炎組(P<0.05);Without stimulation,the PPC of CD154 on T cell in the aged control group was significantly higher than that in the young control group(P<0.05),but lower than that of the aged pneumonia group(P<0.05).
- 術(shù)前輸注供體來(lái)源的IL-12 p35 silenced DC聯(lián)合CD40L mAb,可在一定程度上抑制小腸移植的排斥反應,誘導受體產(chǎn)生免疫耐受。The treatment with IL-12 p35 silenced DCs with anti-CD40L mAb can induce immune tolerance and prolong intestinal allografts survival after transplantation.
- RA患者CD4+T細胞上CD154分子表達增加,CD8+T細胞上CD154分子表達減少,T細胞亞群上可誘導共刺激分子(ICOS)的表達無(wú)明顯變化;CD154 on RA CD4~+T cells was increased but decreased on RA CD8~+T cells. The expression of ICOS on T cell subsets was similar to that of normal control;
- 方法采用流式細胞技術(shù)檢測SLE、RA患者外周血T細胞亞群表面CD28、CD152、誘導性共刺激因子(ICOS)、CD154、CD30和CD95分子表達。Methods Apply flow cytometry to determine the expressions of costimulators CD28,CD152,ICOS,CD154,CD30 and CD95 on T lymphocyte subsets in patients with SLE and RA.
- 目的:研究CD154在膀胱移行細胞癌(TCC)中的表達及其與腫瘤臨床分期和病理分級之間的關(guān)系,并通過(guò)體外細胞培養以及小鼠膀胱腫瘤模型研究CD154的表達對膀胱TCC成瘤性的影響。Objectives: To investigate CD154 expression in transitional cell carcinoma(TCC) of bladder and its correlation with tumor stage and tumor grade,and further to explore its effects on tumorigenesis by in vitro and in vivo experiments.
