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- Results 95%alcohol was the best choice for eluating triptolide. 結果雷公藤內酯醇洗脫率以95%25乙醇為最高。
- Wilforlide A is Leigongteng Duodai's characteristic and active constituent. 雷公藤內酯甲是雷公藤多甙的主要活性成分之一，同時(shí)又是其指示成分。
- Conclusion 95% alcohol may be applicable as the eluent of triptolide. 結論95%25乙醇可作為雷公藤內酯醇的洗脫劑。
- CONCLUSION Finger Citron may obviously increase the content of triptolide. 其余配伍提取液中雷公藤內酯醇無(wú)顯著(zhù)變化。
- Objective To study the influence of eluent of different polarity on triptolide content. 目的研究不同極性洗脫液對雷公藤內酯醇含量的影響。
- Objective To observe the effects of Triptolide on proliferation and apoptosis of erythroleukemia K562 in vitro. 目的探討雷公藤內酯醇對人類(lèi)紅白血病K562細胞株增殖和凋亡的影響。
- The catalytic gas liquid isotope exchange reaction is a good method to prepare tritiated triptolid. 采用催化氣液同位素交換法制備了氚化雷公藤甲素,探討了反應時(shí)間和反應介質(zhì)對反應產(chǎn)額的影響。
- The main pharmacological actions such as anti-inflammatory,immunosuppression and antitumor of triptolide are reviewed. 綜述了關(guān)于雷公藤甲素的抗炎、免疫抑制、抗腫瘤等主要藥理作用的研究進(jìn)展。
- Conclusion: Triptolide can inhibit the proliferation of HeLa cells by induction of cells apoptosis. 結論：雷公藤內酯醇可以通過(guò)誘導腫瘤細胞凋亡而發(fā)揮抗腫瘤作用。
- HPLC method for the determination of triptolide and epitriptolide was established. 建立了HPLC法以測定雷公藤內酯醇與差向異構體表雷公藤內酯醇的含量。
- Abstract:Objective：To investigate the immunoregulation of triptolide on inflammatory mediators of septic rats. 目的：探討雷公藤內脂醇對膿毒癥大鼠血清促炎與抗炎介質(zhì)的調節作用。
- Triptolide notably inhibit the proliferation of A549 cells, arrest A549 cell at S phase and G2/M phase and induce apoptosis of A549 cells. 雷公藤內酯醇能抑制A549細胞的生長(cháng),使其阻滯在S期和G2/M期,并誘導其發(fā)生凋亡。
- OBJECTIVE：To determine triptolide in Tripterygium wilfordii obtained in different season and various parts grown on fujian province. 目的：對福建產(chǎn)的雷公藤不同季節不同部位進(jìn)行雷公藤內酯醇的含量的測定。
- According to a report in 1977, using 0.25 mg/kg of the triptolide obtained from kun ming shan hai tang on L615 mice had very good result. 雷滕素甲，乙，丙在動(dòng)物試驗對腫瘤有很高的活性。1977年報導昆明山海棠中分離得到雷公藤素甲，0.;25毫克/公斤對小鼠L615有很好的效果。
- Conclusion Triptolide notably inhibit the proliferation of A549 cells, arrest A549 cell at S phase and G2/M phase and induce apoptosis of A549 cells. 結論雷公藤內酯醇能抑制A549細胞的生長(cháng),使其阻滯在S期和G2/M期,并誘導其發(fā)生凋亡。
- OBJECTIVE:To determine triptolide in Tripterygium wilfordii obtained in different season and various parts grown on fujian province. 目的:對福建產(chǎn)的雷公藤不同季節不同部位進(jìn)行雷公藤內酯醇的含量的測定。
- METHODS Decocted respectively the Tripterygium wilfordii and the four Chinese crude drugs with water, and evaluated the triptolide by HPLC. 方法4種飲片分別與雷公藤配伍，加水提取，用HPLC測定雷公藤單提液及其配伍提取液中的雷公藤內酯醇。
- It was suggested that Triptolide possesses potent of anti-leukemic cell proliferation and was able to regulate the G1 /S transmit checkpoint of HL60 cells. 雷公藤內酯醇有明確的抗白血病細胞增殖的能力,能干擾HL60細胞G1/S檢測點(diǎn)的轉換。
- Objective Using the collagen-induced arthritis (CIA) rat model,to observe if Triptolide (T_(10)) can induce the apoptosis of synoviocytes of CIA rat model. 目的以膠原誘導的關(guān)節炎(collagen-induced-arthritis,CIA)為動(dòng)物模型,探討雷公藤甲素(Triptolide)能否誘導CIA大鼠滑膜細胞凋亡。
- The expression and activity of the focal adhesion kinase on cultured Raji cells were regulated by Triptolide,and this regulation may be important in the tumor-pathogesis. 雷公藤內酯醇具有抗淋巴瘤細胞增殖效應,并同時(shí)降低FAK含量和活力,提示雷公藤內酯醇抗腫瘤效應可能與抑制黏著(zhù)斑激酶介導細胞信號轉導有關(guān)。
