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- This disease results from an abnormal gene on chromosome 4 which codes for a protein containing increased trinucleotide repeat sequences. 因4號染色體異常編碼引起,該基因編碼的蛋白質(zhì)包括增多的三核苷酸重復序列。
- Trinucleotide repeat diseases 三核苷酸重復疾病
- HD is caused by a trinucleotide repeat expansion in the Huntingtin (Htt) gene; and is one of several polyglutamine (or PolyQ) diseases. 什么是'少年亨廷頓疾病-遺傳性疾病與異常運動(dòng)和心理的惡化'?
- Keywords Huntington disease;HD gene;trinucleotide repeat;dynamic mutation; 關(guān)鍵詞亨廷頓病;HD基因;三核苷酸重復;動(dòng)態(tài)突變;
- Keywords genetic disease;mutation;polyalanine expansion;trinucleotide repeat; 遺傳病;突變;多聚丙氨酸延展;三核苷酸重復;
- trinucleotide repeat expansion mutations 三核苷酸重復片段擴增突變
- trinucleotide repeat expansion mutations(TREM) 三核苷酸重復片段擴增突變
- The expansion of trinucleotide repeats in genome is related to the phthogenesis of several neurodegenerative deseases. 人類(lèi)基因中三核苷酸重復序列拷貝數的異常擴增,可導致多種神經(jīng)系統疾病。
- Expansion of trinucleotide repeats represents an important type of pathogenic mutations. 三核苷酸重復的延展突變是導致遺傳病的重要機制之一。
- Study of the role of RNA-binding proteins in the pathogenic mechanism of trinucleotide repeats expansion diseases using C. elegans as a model organism. 2007教育部顧問(wèn)室95-96年度生物及醫學(xué)科技人才培育先導型計畫(huà)-醫衛分子檢驗領(lǐng)域。
- Molecular anslysis on the CAG trinucleotide repeat of Huntington's disease in Anhui people 安徽入亨廷頓病CAG三核苷酸重復的分子分析
- His disease was complicated by pneumonia. 他的病因肺炎并發(fā)癥而變得更嚴重。
- Keywords Huntington disease;early diagnosis;trinucleotide repeat expansion;genetic anticipation; 亨廷頓舞蹈病;早期診斷;擴增突變;遺傳早現;
- Keywords trinucleotide repeat expansion;psychiatric disorders; 三核苷酸重復序列擴增;精神系統疾病;
- He made a resolution never to repeat the act. 他決心不再采取那種行動(dòng)。
- AG/CT and AAG/CTT are the most frequent motifs,accounting for 84.04% and 35.71% in dinucleotide and trinucleotide repeats,respectively. The potential of the EST-SSRs for designing primers specific to flanking sequences was assessed. AG/CT和AAG/CTT是二、三核苷酸中的優(yōu)勢重復類(lèi)型;分別占二、三核苷酸重復的84.;04%25和35
- Or you can say history repeat itself. 或者說(shuō)也可以說(shuō),歷史經(jīng)常重演。
- What can we do to prevent the disease spreading? 我們能做什么來(lái)防止這種疾病蔓延呢?
- They made me repeat/I was made to repeat the story. 他們逼我又把那事講了一遍。
- John put up a real fight to overcome the disease. 約翰為征服疾病,進(jìn)行了不屈的斗爭。