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- Conclusion LPL is a key enzyme in lipid metabolism and LPL gene knockout can influence the levels of lipid in serum and tissue. 結論LPL是脂代謝的關(guān)鍵酶，LPL(+/-)小鼠血清及組織脂質(zhì)變化顯著(zhù)。
- Abstract: Regulation of specific proteins by phosphorylation is usually overlooked by standard loss-of-function approaches such as RNAi or gene knockout, which simply remove the gene or protein. 摘 要： 常規 R NA 干涉或基因敲除的功能缺失手段僅僅只是簡(jiǎn)單地移除某個(gè)基因或蛋白，而這個(gè)過(guò)程常常會(huì )掩蓋磷酸化對某個(gè)特定蛋白的調節。
- Transgenic or knockout of specific genes have led to the development of rodent models of spontaneous colitis. 轉基因和基因敲除動(dòng)物模型帶動(dòng)了自發(fā)性結腸炎動(dòng)物模型的發(fā)展。
- A full description is given on the structure, the unique tissue specific expression pattern , the factors and mechanisms involved in the expression regulation of the gene of aromatase,CYP19. 綜述了編碼該酶的CYP19基因的結構、獨特的組織特異性表達和調控CYP19基因表達的各種因素及其有關(guān)的調控機制。
- Molecular techniques such as gene knockout partially support the monoamine theory of depression. 諸如基因部分敲除的分子技術(shù)支持抑郁癥的單胺理論。
- We also detected BMD in APN gene knockout mice to evaluate the relationship between adiponectin and bone metabolism. 對骨代謝的初步研究采用檢測小鼠骨密度(BMD)的方式。
- Processes involved in the site-specific effect of probucol on atherosclerosis in apolipoprotein E gene knockout mice. (有關(guān)普羅布考對載脂蛋白E基因敲除小鼠的動(dòng)脈粥樣硬化的位點(diǎn)專(zhuān)一作用)。
- Therefore, CRES may perform unique and tissue specific functions in the reproductive and neuroendocrine systems. 因此 ,CERS在生殖系統和神經(jīng)內分泌系統中的功能也許是獨特的和組織特異性的。
- tissue plasminogen activator gene knockout mice 組織型纖溶酶原激活劑基因敲除小鼠
- It enables a specific gene to be located on a particular restriction enzyme fragment. 它就能使專(zhuān)一的基因被定位于特定的限制性?xún)惹忻盖谐傻钠紊稀?/li>
- In 2002, Anderson, MS reported that Aire could regulate the transcription of many tissue specific antigens in mTECs. 2002年，Anderson，MS等報道了Aire可以調節多種組織特異性抗原在mTECs的轉錄。
- Conclusion: The results shows that no significant alteration on glycometabolism or bone metabolism was found in APN gene knockout mice. 結論：脂聯(lián)素基因剔除小鼠在基礎狀態(tài)下并無(wú)顯著(zhù)的糖代謝和骨代謝異常。
- The 2.2 kb of the MIA promoter contains cis acting elements which can generate tissue specific expression in vivo . 2.;2 kb 的MIA/CD－RAP啟動(dòng)子含有調節M(mǎn)IA/CD－RAP組織特異性表達的順式調控元件
- Methods: We detected the weight and glucose level in APN gene knockout mice and evaluated the ability of glycometabolism by GTT and ITT. 方法：采用長(cháng)期追蹤野生型和該基因剔除純合子小鼠的體重和空腹血糖水平，并進(jìn)行葡萄糖耐量(GTT)和胰島素耐量(ITT)試驗以評價(jià)該小鼠的葡萄糖代謝能力。
- It was clear in RT-PCR that human myocardial specific gene MLC-2V. MLC-2A. a-MHC. CTnT. RT-PCR顯示，移植hEBDs的雞胚心肌中有人心肌特異性的基因MLC-2V、MLC-2A、-MHC、CTnT、ANP與NKx-2.;5等表達。
- It was speculated that the cis acting element in region A might determine the tissue specific expression character of A33 promoter. 推測A區所包含的順式調控元件很可能是決定A33基因組織特異性表達的關(guān)鍵元件 .
- The locomotion of mtm-5 gene knockout group is obviously faster than control group, this suggests that MTM-5 also plays a negative regulation role in the muscle development. mtm-5基因敲除型線(xiàn)蟲(chóng)的運動(dòng)能力明顯比對照組快，暗示其可能與肌肉系統以及整體的發(fā)育存在著(zhù)某種負調控的聯(lián)系。
- Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone. 高同型半胱氨酸血癥誘導同型半胱氨酸在骨骼中通過(guò)與膠原結合的組織特異性沉積，并對骨骼造成不良影響。
- Howeer, uniparental ES cell research faces the biological hurdle of genomic imprinting, in which specific gene expression patterns are dictated by the parental origin. 然而，單系胚胎干細胞研究面臨著(zhù)基因組印跡的生物學(xué)障礙，即特殊的基因表達模式受原始親代的控制。
- This would seem to prevent researchers from making dog "knockouts" lacking a specific gene or engineering dogs that produce mutant forms of a gene. 因為缺少一種特定的基因或能產(chǎn)生突變基因的轉基因狗，研究人員可能無(wú)法進(jìn)行狗基因敲除。
