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- Using the home-made Perl programs, we extracted the concerned bases upstream and downstream of both the initiator codon and the stop codon for analysis. 通過(guò)自編的系列Perl程序,從智人RefSeq數據庫中分別抽取mRNA序列起始密碼子、終止密碼子上、下游一定數目堿基進(jìn)行分析,得出以下主要結論:
- This fragment three flanking end location is in the first translation start codon ATG (+1) up stream 128 bp. 這段片段的3’端起始點(diǎn)在第一個(gè)外顯子里第一個(gè)翻譯密碼子ATG(+l)上游128 bp處。
- The first ATG rule for recognizing the start codon of gene coding sequences is given. 提出了一個(gè)識別基因起始密碼子的第一ATG規則.
- Furthermore, a fragment of 150bp from start codon ATG to 150nt showed the most variation. 從ATG至第150bp區段的核苷酸序列變異頻率最高。
- The complete VP1 gene of CVB2 Yunnan strain had a total length of 846bp and without initiator codon and terminator codon. The highest similarity of VP1 gene with Ohio 1 strain(GenBank logging number:AF081312) nucleotide and amino acid sequence was 98% . CVB2云南分離株VP1基因全長(cháng)約846bp,無(wú)起始密碼及終止密碼,與Ohio-1株(GenBank登錄號:AF081312)核苷酸、氨基酸序列同源性最高為98%25。
- The detection rates of pre-S2 start codon mutation were significantly different in different groups: from 50.00% (HCC), 39.47% (LC), 8.00% (CH), to ASC (0). 前S2起始碼變異在HCC、LC組的檢出率分別為50.;00%25、39
- In human cDNA sequencing projecs, it is vital to know whether the first ATG codon is a real start codon or an in frame Met codon without initiation function. 在人類(lèi)cDNA序列確定全長(cháng)基因的過(guò)程中 ;必須判斷第一個(gè)ATG密碼子是真正的起始密碼子還是框內的非起始作用的甲硫氨酸密碼子 .
- DNA sequencing revealed that the IPNS gene of S. cattleya consists of 963 bp encoding a protein of 321 amino acids with ATG as start codon, TGA as stop codon. 經(jīng)基因序列分析表明牲畜鏈霉菌中IPNS基因;由963bp組成;起始密碼子為ATG;終止密碼子為T(mén)GA;共編碼321個(gè)氨基酸;所克隆的牲畜鏈霉菌IPNS基因編碼蛋白與已知的S.
- The detected ratios of pre-S2 start codon and pre-S deletion mutations were significantly higher in genotype C than in genotype B (43.04% vs 1.23%, 36.71% vs 19.75%, P < 0.05, respectively). C基因型前S2起始碼變異的檢出率為43.;04%25;高于B型的1
- The distance and the composition between the Shine-Dalgarno(SD)sequence and the start codon have, profound effect on the expression of prochymosin gene causing a 15fold difference. Shine-Dalgarno序列與起始密碼子之間的距離與組成對凝乳酸原基因表達有明顯的影響,可導致其表達水平有15倍之差。
- The initiation codon represents the first amino acid, N-formyl methionine, at the N terminus of the polypeptide. 即編碼多肽N-端第一個(gè)氨基酸即甲硫氨酸(N-甲酸化的)的密碼子。
- A vitamin D receptor gene polymorphism in the translation initiation codon: effect on prote in activity and relation to bone mineral density in Japanese women. 更難理解的是為什么這些等位基因有時(shí)存在,有時(shí)不存在,有時(shí)甚至是相反的結果。
- A deletion of adenosine (A), at -241 (relative to initiation codon ATG), designated as Del(A) allele, was found in Laiwu compared with Yorkshire (GenBank accession number DQ463321-22). 克隆了豬DGAT1 5’調控區的部分序列(737 bp),在-241bp(相對于起始密碼子ATG)發(fā)現一處由單個(gè)腺嘌呤(A)缺失產(chǎn)生的新SNP位點(diǎn)(定義為等位基因Del(A) ) (GenBank收錄號:DQ463321-22);
- In this case, let's start earlier. 既然這樣,我們就早點(diǎn)開(kāi)始。
- I hope you can pardon his badness and let him start all over again. 希望您能原諒他的不好,讓他從新開(kāi)始。
- Effect of the Flanking Sequence Architecture of AUG,a Initiator Codon on Gene Expression Level in Rice 起譯密碼子AUG側翼序列對水稻基因表達水平的影響
- The autumn or winter term start in September. 秋季或冬季學(xué)期九月份開(kāi)始。
- It seems that his life is off to a new start. 看來(lái)他的生活有了新開(kāi)端。
- How do you get start in that line of work? 你是怎么開(kāi)始干那一行的?
- She woke up with a start when the door slammed. 關(guān)門(mén)聲把她驚醒了。