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- 目的探討柴胡皂苷-d(saikosaponin-d,SSd)對脂多糖(lipopolysaccharides,LPS)作用后腎小球系膜細胞(mesangial cell,MC)增殖及細胞外基質(zhì)(extracellular matrix,ECM)的異常增生的影響,為腎小球硬化的防治提供實(shí)驗依據。Objective To investigate the effects of saikosaponin-d (SSd) on glomerular mesangial cells (MCs) proliferation and hyperplastic extracellular matrix (ECM) induced by lipopolysaccharide (LPS) to provide experimental proof for its use in prevention and treatment of glomerulosclerosis.
