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- The results showed that 27%(23/85) PZA-resistant isolates had pncA mutations which altered the primary amino acid sequence of pyrazinamidase. PZA耐藥株有27%25(23/85)發(fā)生了pncA基因突變,從而導致吡嗪酰胺酶基本氨基酸序列的改變,突變分布在pncA基因開(kāi)讀框架17-546位的核苷酸。
- pyrazinamidase 吡嗪酰胺酶
- PZase (=pyrazinamidase) 吡嗪酰胺酶
