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- Poloxamer 188 can also inhibit inflammation and resist thrombus. 泊洛沙姆188具有抑制炎癥和抗血栓形成作用,注射使用具有一定的安全性;
- When add SLS、poloxamer or sodium deoxycholate , the solubility were decreased. 加入SLS、泊洛沙姆、脫氧膽酸鈉后，溶解度較二元體系下降。
- The ear pills were prepared with poloxamer and PEG as basesrespectively. 采用水溶性非離子型表面活性劑聚醚作基質(zhì)制備吡哌酸耳用滴丸。
- For brain glioma therapy, BCNU-loaded nanoparticles were prepared using Pluronic F68 as surfactant. 以Pluronic F68作表面活性劑,制備了包載卡氮芥(BCNU)的聚乳酸納米微粒,用于腦神經(jīng)膠質(zhì)瘤的治療。
- The FasL+ chondrocytes mixed with Pluronic F127 were injected subcutaneously into abdomen wall in allogenic porcine. 取FasL+的軟骨細胞與可注射性生物材料PluronicF127混合,注射于同種異體豬的腹壁皮下。
- Pluronic F 127 can be used for a carrier for bioactive factors to modify bio derived material. 生物衍生骨經(jīng) Pluronic F- 12 7表面修飾后具有良好的細胞相容性 ,可作為負載生物活性分子的載體修飾生物衍生骨。
- Pluronic F-127 can be a safe and effective vehicle of chondrocytes implantation. Pluronic F-127可作為工程化軟骨細胞安全有效的載體。
- Pluronic group: 25% Pluronic F-127 was poured into the articular cartilage defects. 單純支架組只將25%25Pluronic F-127注入股骨內髁軟骨缺損區。
- Objective To synthesize copolymers composed of polyacrylic acid and poloxamer 407,and investigate its thermo-sensitive gelling properties in situ. 目的制備丙烯酸和泊洛沙姆407構成的共聚物,研究其溫度敏感的原位膠凝性質(zhì)。
- Objective：To determine the therapeutic effects of Norcantharidin Poloxamer 407 in intratumoral administration to primary liver cancer. 目的：探討去甲斑蝥素-泊洛沙姆407緩釋制劑局部注射治療肝癌的療效。
- Forthly,we seleced the optical concentration of non-inonic sufactant poloxamer 188,which could perfectly prevent protein aggregation at 1.0mg/ml. 第四，我們挑選出了非離子表面活性劑泊洛沙姆188的最佳濃度。當其濃度為1.;0mg/ml時(shí)能夠很好地抑制蛋白質(zhì)的聚合。
- Conclusion Dissolution in vitro of curcumin can been increased significantly by solid dispersions prepared with poloxamer 188 as carriers. 結論采用泊洛沙姆188制備的固體分散體能顯著(zhù)提高姜黃素的體外溶出度。
- In 1. 5 L Celligen bioreactor, when pluronic F-68 concentration is 0. 10%(W/V) in medium and agation speed is 70r/min the hybridoma cell can grow normally. 在1.;5升GelliGen生物反應器中;培養基添加0
- The dissolution rates in vitro of ursolic acid solid dispersion were obviously raised, and PVP-k30 was a better carrier in increasing the dissolution rate than Poloxamer 188. 以聚乙烯吡咯烷酮為載體制備的固體分散體溶出速度快于泊洛沙姆。
- At last,we develope a stable aqueous rhGH formulation comprising 5mM histidine,1.0mg/ml poloxamer 188,2.5mg/ml phenol,1.5%(v/v) glycerin and 4.0mg/ml NaCl at pH5.6. 基于以上研究我們研究開(kāi)發(fā)出了一種穩定的重組人生長(cháng)激素液體制劑，含有5mM組氨酸、1.;0mg/mlpoloxamer188、2
- Desai SD,Blanchard J.Evaluation of Pluronic F127 sustained-release ocular delivery systems for pilocarpine using the albino rabbit eye model[J].J Pharm Sci,1998,87(10):1190. 魏剛;徐暉;鄭俊民.;原為凝膠的形成機制及在藥物控制釋放領(lǐng)域的應用[J]
- Method: Solid dispersion systems of ursolic acid in PVP-K30 or Poloxamer 188 were prepared by co-evaporation of the drug and PVP-K30 or Poloxamer 188 ethanol solution. 方法：選擇聚乙烯吡咯烷酮K30、泊洛沙姆188兩種載體，用溶劑法制備烏索酸固體分散體；
- CLSM system can accurately reflect cytosolic concentration of free Ca 2+ labeled by Fluo-3/AM and Pluronic F-127. TCDD may increase [Ca 2+]_ i, then make some impairment to the heart function of the neonate rats. 應用Fluo3/AM和PluronicF127結合CLSM技術(shù)可以精確的反映細胞內游離鈣離子濃度,TCDD可能通過(guò)某種機制增加心肌細胞[Ca2+]i,從而對乳鼠心臟功能產(chǎn)生一定損傷。
- Using PTX-resistant SKOV-3 tumor cells as an in vitro model of MDR tumor cells, we demonstrated that Pluronic micellar PTX (i.e. P105/PTX or P105L101/PTX) were able to reverse PTX-resistant SKOV-3 tumor cells compared with free PTX solution. 并采用人卵巢癌多藥耐藥細胞SKOV-3/PTX作為體外多藥耐藥的腫瘤細胞模型,評價(jià)紫杉醇Pluronic膠束逆轉腫瘤多藥耐藥性的作用。
- The critical micelle concentration (CMC) of Pluronic block copolymer F127 in aqueous solutions and the micellar structure are determined by UV and fluorescence spectroscopy as well as viscosity technology in the presence of phenol. 通過(guò)紫外 -可見(jiàn)光譜、熒光光譜和黏度等技術(shù)測定在苯酚存在下 ,Pluronic嵌段共聚物F12 7水溶液的臨界膠束濃度 (CMC)以及膠束結構的變化 ,考察苯酚濃度cph對膠束增溶蒽的影響。
