This enhancing activity of lipase might be attributed to the structural changes of the stratum corneum by some special biochemical reactions of lipase to lipids. 胰脂肪酶可能直接作用于角質(zhì)層脂質(zhì)部分,通過(guò)某種特異的生物化學(xué)反應,使其構造疏松或變?yōu)闊o(wú)序狀態(tài),從而促進(jìn)藥物的透皮吸收。