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- 目的:通過(guò)研究?jì)绕に?1(endothelin-1,ET-1)在口腔粘膜下纖維化中mRNA的表達,探討ET-1與OSF(oral submucous fibrosis)病變發(fā)生發(fā)展的關(guān)系。Objective: To study the expression of endothelin-1 (ET-1) in oral submucous fibrosis(OSF), so as to investigate its role in the pathogenesis of OSF.
- 目的:探討丹參是否能夠通過(guò)改善檳榔損傷的血管內皮細胞(endothelial cell,EC)的功能而對口腔黏膜下纖維性變(oral submucous fibrosis,OSF)產(chǎn)生治療作用。PURPOSE: To discuss the mechanism of salvia miltiorrhizae injection (SMI)on oral submucous fibrosis (OSF) through improving the function of the vascular endothelial cell (EC) damaged by aqueous areca nut extract (AANE).
- 口腔癌缺失(deleted in oral cancer-1,DOC-1)基因是Todd等于1995年利用倉鼠口腔癌模型分離和證實(shí)的一個(gè)候選抑癌基因，p12蛋白是其編碼的具有腫瘤生長(cháng)抑制功能的蛋白。Deleted in oral cancer-1 (DOC-1) is a novel putative oral tumor suppressor genes identified and isolated from the hamster oral cancer model in 1995, p12 protein is a tumor growth suppressor coded by DOC-1. As a new candidate tumor suppress gene, up to the present its some functions and mechanisms have been studied.
- 盡管采用了以外科手術(shù)切除為主,協(xié)同運用化療或放療手段的綜合治療,但口腔鱗癌(Oral Squamous Cell Carcinoma, OSCC)患者的總體生存率并無(wú)顯著(zhù)提高,尤其是臨床中、晚期患者,其療效仍不理想。Despit of comprehensive treatments with primary surgery integrated with chemiotherapy or radiotherapy, the survival rate of the patients with Oral Squamous Cell Carcinoma(OSCC) has not been improved evidently, especially advanced OSCC. Dendritic cells (DCs), which are uniquely the most potent professional antigens-presenting cells(APCs) with the capacity to activate naive T lymphocytes, are considered to be promising adjuvants for immunity against cancer.
- 酕醄
