o fluorotoluene was obtained from o tolidine through Schiemann reaction. o fluorotoluene was then chloridized and hydrolyzed,in turn,to give 52% of o fluorobenzonitrilc with a purity of 99%.
英
美
- 以鄰甲苯胺為原料；經(jīng)希曼反應合成了鄰氟甲苯；再經(jīng)氯化、水解、肟化和脫水4步反應生成了鄰氟苯甲腈；考察了每步反應對合成的影響；總收率34.；4%25；產(chǎn)品純度達到了99%25以上
