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- The finding of Neurotrophic Factors( NTF) bring about new hope for SCI. 神經(jīng)營(yíng)養因子(Neurotrophic Factors,NTF)的發(fā)現為脊髓損傷的治療帶來(lái)了新的希望。
- In the process of development and regeneration of nervous system, it act as neurotrophic factor. 在神經(jīng)系統發(fā)育和再生過(guò)程中,肝細胞生長(cháng)因子作為神經(jīng)營(yíng)養因子發(fā)揮作用。
- To date, the most potent of these chemicals is glial-cell-line deried neurotrophic factor (GDNF). 迄今為止,在這些化學(xué)物質(zhì)之中效果最好的就是神經(jīng)膠質(zhì)細胞源性的神經(jīng)營(yíng)養因子。
- Objective To investigate the role of ciliary neurotrophic factor (CNTF) in injury of central neuron. 目的研究睫狀神經(jīng)生長(cháng)因子(CNTF)在中樞神經(jīng)元抗損傷中的作用及機制。
- Objective To investigate the effects of glial cell line derived neurotrophic factor in human inflammatory pulp. 目的探討膠質(zhì)源性神經(jīng)營(yíng)養因子(GDNF)在人炎癥牙髓中的表達及意義。
- Objective To explore the changes of brain-derived neurotrophic factor(BDNF) after repeated febrile seizures (FS). 目的探討大鼠反復高熱驚厥(FS)后腦源性神經(jīng)營(yíng)養因子(BDNF)的變化。
- In the process of development and regeneration of nervous system,it act as neurotrophic factor. 在神經(jīng)系統發(fā)育和再生過(guò)程中,肝細胞生長(cháng)因子作為神經(jīng)營(yíng)養因子發(fā)揮作用。
- Synaptic actions of brain-derived neurotrophic factor (BDNF) are "gated"by cAMP, but the underlying molecular mechanisms remain unclear. 腦源性神經(jīng)營(yíng)養因子(BDNF)的突觸活動(dòng)受到環(huán)腺苷酸(cAMP)的門(mén)控調節,但是這種調節機制還不清楚。
- To study the ultr a structure localization of Schwann cell (SC) derived neurotrophic factor (SDNF) in Schwann cells. 目的觀(guān)察許旺細胞源神經(jīng)營(yíng)養因子的超微結構定位,探索其在神經(jīng)、皮膚和肌肉中的分布以及神經(jīng)損傷前后量的變化。
- Ma ZC, Wu XL, Pan W, et al.Expression of brain-derived neurotrophic factor receptor trkB on NIH 3T3 cells[J].Life Sci Res, 2001, 5(3):265-9. [6]馬仲才;吳曉蘭;潘衛;等.;腦源性神經(jīng)營(yíng)養因子受體trkB在NIH 3T3細胞上的表達[J]
- Nerve growth factor is the typical representative of neurotrophic factor family,which has conspicuous effect on nervous system. 神經(jīng)生長(cháng)因子(NGF)是神經(jīng)營(yíng)養因子家族的典型代表,為一種堿性蛋白,是神經(jīng)系統中最重要的生物活性分子之一,有明顯的中樞效應。
- The second approach is based on animal studies showing that ciliary neurotrophic factor (CNTF) can protect striatal cells from death. 第二種治療方式是根據動(dòng)物實(shí)驗的結果:睫狀神經(jīng)營(yíng)養因子(CNTF)能保護紋狀體神經(jīng)元免于死亡。
- Objective To study the effect and mechanism of ciliary neurotrophic factor (CNTF) on the spinal motor neuron death and degeneration following peripheral nerve lesion in the rat. 目的探討周?chē)窠?jīng)損傷后睫狀神經(jīng)營(yíng)養因子(CNTF)對脊髓運動(dòng)神經(jīng)元的保護作用及其作用機理。
- Objective To study the protective effects of Schwann cell derived neurotrophic factor (SDNF) on motoneurons of spinal anterior horn from spinal root avulsion induced cell death. 目的研究雪旺細胞源神經(jīng)營(yíng)養因子(SDNF)對臂叢神經(jīng)根性撕脫所致前角運動(dòng)神經(jīng)元死亡的保護作用。
- Brain-derived neurotrophic factor (BDNF) was shown to induce antiapoptotic mechanisms after stroke and to reduce infarct size and secondary neuronal cell death. 腦源性神經(jīng)營(yíng)養因子(BDNF)被顯示了卒中后可誘導抗凋亡機制并減少梗塞面積以及繼發(fā)神經(jīng)細胞死亡。
- Brain-derived neurotrophic factor (BDNF) is one of the neurotrophic factors.BDNF has many biological effects on neurons of peripheral and central nervous system. 摘要腦源性神經(jīng)營(yíng)養因子(BDNF)是神經(jīng)營(yíng)養因子家族中的一員,BDNF對周?chē)椭袠猩窠?jīng)元有廣泛的生物學(xué)作用。
- Objective:To prepare stable, small-sized injectable sustained-release nanoparticles harboring brain-derived neurotrophic factor (BDNF) and to evaluate its drug releasing process. 目的:制備穩定性高、粒徑小的腦源性神經(jīng)營(yíng)養因子(BDNF)緩釋注射納米粒,并評價(jià)其釋藥過(guò)程。
- Kim H, Li Q, Hempstead BL, et al.Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells[J]. 孫春艷,胡豫,吳濤,等.;多發(fā)性骨髓瘤細胞腦源性神經(jīng)營(yíng)養因子對血管新生作用的研究[J]
- Preincubation of the cultures with ciliary neurotrophic factor (CNTF) for 24 h promoted neuronal survival and decreased the LDH efflux and the level of NO induced by ionomycin. 提前24 h給予不同濃度CNTF, 均能提高神經(jīng)元的存活率, 減少LDH漏出, 其作用呈劑量依賴(lài)性;CNTF可降低ionomycin引起的NO含量升高;
- To construct a recombinant plasmid containing protein transduction domain(PTD) and brain derived neurotrophic factor(BDNF) fusion gene and express in E. 構建含蛋白轉導結構域(PTD)與腦源性神經(jīng)營(yíng)養因子(BDNF)融合基因的質(zhì)粒,并在大腸肝菌中表達。