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- Mammalian Mitochondrial DNA(mtDNA) control region consists of central domain, ETAS domain and CSB domain. 哺乳動(dòng)物線(xiàn)粒體DNA(mitochondrialDNA,mtDNA)控制區由中央保守區、ETAS區和CSB區構成。
- Objective:To understand large scale deletion mutation in mitochondrial DNA(mtDNA) and its significance. 目的:了解線(xiàn)粒體DNA大片段缺失突變及其意義。
- Objective To simplify the DNA sequencing method and optimize the conditions for mitochondrial DNA (mtDNA) sequencing. 目的簡(jiǎn)化DNA測序方法,優(yōu)化條件,以適用于線(xiàn)粒體DNA的測序。
- Mitochondrial DNA(mtDNA)and telomere are the primary DNA markers used in deducing individual age in recent years. 目前用于年齡推斷研究的DNA標記主要是線(xiàn)粒體和端粒。
- Considering of the high mutative rate of the coding regions and the conservative heritance of the noncoding regions in human mitochondrial DNA (mtDNA). 針對人類(lèi)mtDNA編碼區突變率高和非編碼區遺傳保守的特點(diǎn),對利用mtDNA分析人類(lèi)母系血緣關(guān)系進(jìn)行了初步的探索。
- Objective To detect the microsatellite instability (MSI) of mitochondrial DNA (mtDNA) in lung squamous carcinoma and to investigate its significance in carcinogenesis. 目的分析肺鱗癌患者癌組織線(xiàn)粒體DNA(mitochondrial DNA,mtDNA)非編碼D-環(huán)區序列的微衛星不穩(mitochondrial microsatellite instability,mtMSI)現象并探討其意義。
- The application of restriction fragment length polymophism(RFLP) of mitochondrial DNA(mtDNA) in the study of genetic diversity of domestic animals was summarized in this article. 對線(xiàn)粒體DNA限制性片段長(cháng)度多態(tài)性(RFLP)在家養動(dòng)物遺傳多樣性研究中的應用現狀進(jìn)行了綜述,并對其應用前景進(jìn)行了展望。
- In this article,we review the relationship between mitochondrial DNA (mtDNA) and carcinogenesis of cancer cells.The possible mechanisms are also discussed. 本綜述重點(diǎn)討論線(xiàn)粒體DNA的損傷與突變在細胞癌變中的地位和可能的作用機制。
- Mitochondrial DNA (mtDNA) is very stable, changing only gradually as it is handed down the generations, which means it is an excellent yardstick for genealogy. 粒線(xiàn)體DNA非常穩定,就算世代傳遞也只會(huì )緩慢改變,因此可以成為絕佳的血緣判斷標準。
- As the only extrachromosomal DNA, mitochondrial DNA (mtDNA) has been shown to play a central role in oxidative phosphorylation (OXPHOS) and adenosine triphosphate synthesis, which decide the activities of cells. DNA 是輻射誘導增殖細胞死亡的主要靶點(diǎn),線(xiàn)粒體DNA(mitochondrial DNA, mtDNA)作為惟一的核外遺傳物質(zhì),其編碼基因參與細胞氧化磷酸化(oxidative phosphorization, OXPHOS)和能量代謝,與細胞的存亡息息相關(guān)。
- In this system, cloned maize mitochondrial DNA(mtDNA) is served as template. this is the first established cell-free system for in vitro transcription of cloned DNA with a plant RNA polymerase B. 這是首次用克隆化DNA為模板,以植物RNA聚合酶B建立起的無(wú)細胞離體轉錄系統。
- The mitochondrial DNA (mtDNA) of piranhas has an extremely high mutation rate so this was used as a basis for reconstructing the evolution of the 28 modern species of this carnivorous fish. 水虎的線(xiàn)粒體DNA有極高的突變幾率,這導致演化到現在有28種水虎食肉魚(yú)存在。
- mitochondrial DNA (mtDNA) control region 線(xiàn)粒體控制區
- Objective To analyze mitochondrial DNA polymorphism of district of Lubunour at the Bronze Age in Xinjiang. 目的 :通過(guò)新疆羅布諾爾地區銅器時(shí)代古代居民 m t DNA多態(tài)性分析 ,探討新疆境內古代歐洲人種成分的來(lái)源。
- Compared with the normals, the amount of the mitochondrial DNA were decreased universally in the patients with AD. (2)和正常老人相比,AD患者中線(xiàn)粒體DNA的數量普遍減少;
- Objective:To study the possible relationship between mitochondrial DNA point mutations and hereditary ataxia. 目的:探索線(xiàn)粒體DNA點(diǎn)突變與遺傳性共濟失調的關(guān)系。
- The strongest support that mitochondrial DNA offers for the African-origin hypothesis may not depend on trees. 線(xiàn)粒體DNA提供非洲起源說(shuō)假設的最強而有力支持也許不是取決于族譜。
- Conclusion:The point mutation in this area of mitochondrial DNA might not be related hereditary ataxia. 結論:遺傳性共濟失調的發(fā)生、發(fā)展可能與該區域點(diǎn)突變無(wú)關(guān)。
- Ancient mutations in mitochondrial DNA are the same as those found in the cells of many tumors. 而在線(xiàn)粒體DNA中的遠古突變和許多瘤細胞中發(fā)現的情況是一樣的。
- From our results,mitochondrial DNA mutation may be one of major factors in aminoglycoside antibiotic induced deafness. 提示線(xiàn)粒體DNA點(diǎn)突變是導致該家系致聾的主要因素之一。