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- Kallikrein is a kind of endopeptidase. 激肽釋放酶是一種內切蛋白酶。
- Another example was the alterations seen in kallikrein proteolysis.Dr. 另一個(gè)例子則是在微血管增滲酶蛋白質(zhì)分解中所看到的改變；
- The human tissue kallikrein is a subgroup of serine proteinase family wich contains 15 genes. 人組織型激肽釋放酶基因家族(kallikreins,KLK)是絲氨酸蛋白酶家族的一個(gè)亞群。
- The kallikrein system, which produces the potent vasodilator bradykinin, is beginning to be studied. 血管舒緩素系統產(chǎn)生強力的血管擴張物質(zhì)緩激肽，有人正開(kāi)始這種研究。
- Through the preliminary optimization of the purification condition, we got high purity of pancreas kallikrein product. 通過(guò)純化條件的初步優(yōu)化，最終得到胰K純品，收率大于85%25。
- In this paper, we describe the structure, quality, enzyme assay, preparation and clinical practice of kallikrein. 本文概述了激肽釋放酶的結構、性質(zhì)、活力測定、制備及臨床應用等內容。
- Fluorescent labeled PTD-kallikrein and Kallikrein were incubated with different types of cells. 將熒光標記的PTD-kallikrein及Kallikrein分別孵育不同細胞，在熒光顯微鏡下觀(guān)察兩種熒光物質(zhì)對生物膜的通透能力。
- Objective:To explore the possibility of the simultaneous extraction of urokinase and kallikrein. 目的:探討尿激酶及激肽釋放酶同時(shí)提取的可能性。
- It was presumed that KBP may playa role in the regulation of metabolism of tissue kallikrein on the level of biosynthesis and excretion. 推測KBP可能在合成和分泌的水平上,對組織激肽釋放酶的代謝及活性起調節作用。
- After screening, one interesting gene was found, human kallikrein 8 (KLK8), a member of human tissue kallikrein gene family. 經(jīng)過(guò)篩選后，發(fā)現一個(gè)有趣的基因-人類(lèi)第八號激肽釋放酶，它是屬于人類(lèi)組織激肽釋放酶基因家族中的一員。
- The purified KBP and human tissue kallikrein forms a 92 KDa SDS- and heat-stable complex. The complex formation is inhibited by the antibody in a dose dependent manner. 純化的KBP特異地和~(125)I-HUK結合成92KDa的復合物,復合物的形成具有明顯的特異性,KBP不能和前激肽釋放酶結合。
- OSCS-containing heparin and synthetically derived OSCS induced hypotension associated with kallikrein activation when administered by intravenous infusion in swine. 在豬上靜脈用OSCS污染的肝素和合成的OSCS后，能使激肽釋放酶激活，血壓下降。
- It inhibits above all plasmin, kallikrein, trypsin, chymotrypsin and urokinase but not carboxypeptidase A and B, papain, pepsin, subtilisin, thrombin and factor X. 抑制所有的纖維蛋白溶酶、激肽釋放酶、胰蛋白酶、胰凝乳蛋白酶和尿激酶，但不包括羧肽酶A和B、木瓜蛋白酶、胃蛋白酶、枯草菌蛋白酶、凝血酶和X因子。
- The average yield and enzyme activity extracted by SP resin were compared with those by 113 resin, J_2 resin and Amberlite CG50. The experiment showed that kallikrein in the mother solution in which elastase had been removed by SP resin could be prepared. 同時(shí)還將SP樹(shù)脂與國內生產(chǎn)彈性酶的J_2樹(shù)脂、113樹(shù)脂及Amberlite CG50進(jìn)行了比較。 實(shí)驗結果表明:利用SP樹(shù)脂吸附彈性酶后的母液仍可回收胰激肽釋放酶。
- Objective To investigate the effect of recombinant aden o-associated virus vector(AVV) expressing the human tissue kallikrein(HK)ge ne (rAVV/HK) on human umbilical vein endothelial cells(HUVECs) in vitro. 目的 探討重組人組織型激肽釋放酶 (HK)基因腺相關(guān)病毒載體 (rAVV/HK)對體外培養的人臍靜脈內皮細胞 (HUVECs)作用。
- The purification of kallikrein using CTAB/hexanol/octane reverse micelles extraction has been studied and optimized,under various aqueous pH values, ionic strength and species, CTAB concentration and co-surfactant concentration. 研究了用十六烷基三甲基溴化銨(CTAB)/正己醇/正辛烷反膠束溶液萃取和反萃取商業(yè)用胰激肽原酶時(shí),水相pH值、離子強度和種類(lèi)、CTAB濃度和助表面活性劑濃度等因素對分離效率的影響,并從反膠束微觀(guān)結構給予解釋。
- The accumulated bicarbonate in the vitreous causes increasingly alkaline conditions that precede activation of the kallikrein pathway, a component of the innate inflammatory response. 玻璃體內累積的碳酸鹽導致內環(huán)境不斷堿化，進(jìn)而激活了激肽釋放酶通路，這一通路是炎癥反應的組成部分。
- Lab research and clinical application of cerebral ischemia from recent years implied that one member of KKS---Tissue kallikrein (TK) has identified protective effects on ischemic brain tissues. KKS系統中主要成分之一激肽釋放酶又可分為組織型和血漿型兩類(lèi)。
- The purification of kallikrein was improved by means of macro-porous anion-exchange resin.The purified product had specific activity 6 timeshigher than the crude one.The purification recovery was 90%. 應用國產(chǎn)大孔型強堿性陰離子交換樹(shù)脂純化激肽釋放酶,精制回收率為90%25,精品平均比活力比粗品提高6倍,比有機溶劑沉淀法為優(yōu)。
- Keywords brain ischemia;kallikrein;bradykinin; 腦缺血;激肽釋放酶;緩激肽;
