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- The ionotropic glutamate receptor antagonists D-AP5 and CNQX could not fully block the action of ACM. 離子型谷氨酸受體拮抗劑D-AP5和CNQX不能完全阻斷條件培養基的作用。
- Glutamate receptors are divided into two subtypes,i.e.,ionotropic glutamate receptor(iGluR)and metabotropic glutamate receptor(mGluR). 谷氨酸是中樞神經(jīng)系統最主要的興奮性神經(jīng)遞質(zhì),其受體共分為兩大類(lèi):離子型及代謝型,兩者均廣泛分布于中樞神經(jīng)系統。
- INFLUENCE OF IONOTROPIC GLUTAMATE RECEPTOR ANTAGONIST ON Fos PROTEIN EXPRESSION IN MEDULLA OBLONGATA OF THE RAT AFTER MECHANICAL DENTAL PULP EXPOSURE 谷氨酸離子型受體拮抗劑對大鼠機械穿髓誘導的延髓Fos蛋白表達的影響
- LOCALIZATIONS OF IONOTROPIC GLUTAMATE RECEPTOR, GABA A RECEPTOR AND GLYCINE RECEPTOR IN THE CAUDAL SUBNUCLEUS OF THE SPINAL TRIGEMINAL NUCLEUS AND SPINAL CORD IN THE RAT 大鼠三叉神經(jīng)尾側亞核和脊髓內離子型谷氨酸受體、GABA_A受體和甘氨酸受體的分布
- Keywords Fluorescence resonance energy transfer （FRET）;Cyan fluorescent protein （CFP）;Yellow fluorescence protein （YFP）;Ionotropic glutamate receptor （iGluR）;Protein interaction; 關(guān)鍵詞熒光共振能量轉移;青熒光蛋白;黃熒光蛋白;親離子型谷氨酸受體;蛋白相互作用;
- There are two classes of glutamate receptors: ionotropic(iGluRs) and metabotropic(mGluRs). 谷氨酸受體有促離子型受體和促代謝型受體兩種類(lèi)型。
- DAO is expressed in the human brain, where it oxidizes D-serine, a potent activator of NMDA glutamate receptor. DAO表達在人的大腦中，它可以氧化D-絲氨酸，后者則是一個(gè)強力的NMDA谷氨酸受體激活劑。
- AIM To study the changes and effects of metabotropic glutamate receptor subtype 2 (mGluR2) in diffuse brain injuries (DBI) coupled with secondary brain insults (SBI) in rats. 目的 研究彌漫性腦損傷 (diffusebraininjury;DBI)及其合并二次腦損傷 (secondarybraininsults;SBI)后大鼠腦皮層代謝性谷氨酸受體 2亞型 (mGluR2 )的變化及其意義 .
- AIM To study the changes and effects of metabotropic glutamate receptor subtype 4 (mGluR4) after diffuse brain injuries (DBI) coupled with secondary brain insults (SBI) in rats. 目的 研究彌漫性腦損傷 (DBI)及其合并二次腦損傷 (SBI)后大鼠腦皮層代謝型谷氨酸受體亞型 4(m Glu R4)的變化及意義 .
- Howlett found the fruit fly's metabotropic glutamate receptor (DmGluRA) gene, when mutated, increased the excitability of the neuron by preventing PI3K from doing its job. 赫爾特發(fā)現當果蠅的親代謝性谷氨酸鹽受體基因發(fā)生突變時(shí)，將通過(guò)阻止PI3K的作用來(lái)增加神經(jīng)元的興奮性。
- Tra2 is an SR-like protein that has several isoforms and, regulates the alternative pre-mRNA splicing of many important genes, including the glutamate receptor. Tra2（splicing factor Transformer-2）是一種SR相關(guān)蛋白的選擇性剪接因子，有多種亞型，Tra2參與包括谷氨酸受體在內的很多重要基因前體mRNA的選擇性剪接。
- During both in vivo and in vitro development, CGC depend on the activity of the NMDA glutamate receptor subtype for survival and full differentiation [3]. 在體內和體外發(fā)育過(guò)程中，小腦顆粒細胞依賴(lài)于N-甲基-D-天冬氨酸(NMDA)谷氨酸鹽受體亞型的活性而生存和完全分化。
- More precisely, they block the action of a form of glutamate receptor known as the NMDA receptor, which plays a critical role in brain development, learning, memory and neural processing in general. 說(shuō)得更精確些，這些藥物阻斷了一種叫做NMDA型的麩胺酸受體，該受體對于大腦的發(fā)育、習、憶以及一般的神經(jīng)活動(dòng)都扮演著(zhù)舉足輕重的角色。
- The N-methyl-D-aspartate receptor (NR), a subtype of ion-tropic glutamate receptor, provides sites for phosphorylation and for channel blocking. NRs are composed of NR1 and NR2A-D subunits. 現已發(fā)現NMDAR至少存在7個(gè)亞單位,即NR1亞單位、4種NR2亞單位(分為NR2A、NR2B、NR2C和NR2D)以及2種NR3亞單位。
- Further pharmacological experiments revealed that S100B secretion was critically dependent on presynaptic release of neurotransmitter and activation of metabotropic glutamate receptor 3. 進(jìn)一步喲來(lái)實(shí)驗揭示了S100B釋放是一種突觸前神經(jīng)遞質(zhì)釋放的方式，并且依賴(lài)于代謝型谷氨酸受體3的激活。
- Glutamate receptors can be divided into two major classes: AMPA and NMDA receptors. 谷氨酸受體主要可以分為兩大類(lèi)：AMPA受體和NMDA受體。
- The glutamate receptor interacting protein 1 (GRIP1) is a scaffolding protein in postsynaptic density (PSD), tethering AMPA receptors to other signaling proteins. GRIP1可以直接與AMPA受體相互作用并將之與其它信號蛋白聯(lián)結在一起。
- Glutamate is a primary excitatory neurotransmitter and responsible for mediating a broad range of nervous system functions through glutamate receptors. 目的谷氨酸是一種重要的興奮性神經(jīng)遞質(zhì),通過(guò)體內的谷氨酸受體參與神經(jīng)系統多種功能的調節。
- Agents that directly activate “AMPA-type” glutamate receptors, which work in concert with NMDA receptors, are also under active investigation. 另外有一種稱(chēng)為AMPA型的麩胺酸受體，可與NMDA受體攜手合作；直接刺激AMPA受體的藥劑，目前也正積極研究當中。
- For the past year, I have been working with a subset of neuronal glutamate receptors via voltage clamping on Xenopus oocytes. 過(guò)去的一年里，我一直在研究在蛙卵上神經(jīng)元谷氨酸受體的一個(gè)子集通過(guò)電壓箝位的現象。
