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- Aminoguanidine (AMG), a specific inducible NO synthase inhibitor (100 M, 1 mM), inhibited the effect of LPS, while 10M AMG did not inhibit the effect of LPS. iNOS特異性抑制劑AMG孵育LPs處理過(guò)的主動(dòng)脈環(huán)1小時(shí)，對主動(dòng)脈低反應的抑制作用呈濃度依賴(lài)性，roo林M和lmM的AMG能完全取消LPS引起的主動(dòng)脈環(huán)的低反應性，10“M的AMG則沒(méi)有這個(gè)效果。
- Kapinya KJ,Lowl D,Futterer C,et al.Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent[J].Stroke,2002,33(7):1889. 李繼慶;張聯(lián)峰;王洋松;等.;異氟醚預處理對大鼠全腦缺血再灌注損傷的保護作用[J]
- inducible NO synthase 誘生一氧化氮合酶
- Observed the effects of mRNA transcriptional inhibitor Actinomycin D, protein synthesis inhibitor Actidione and NO synthase(NOS) inhibitor N-monomethyl-L-arginine(L-NMMA) on the activity of iNOS and intracellular GSH in mouse peritoneal macrophages. 2觀(guān)察 m RNA轉錄抑制劑、蛋白質(zhì)合成抑制劑和 NOS抑制劑對巨噬細胞 i NOS活性和細胞內 GSH水平的影響 ;
- Nitric oxide can be produced in plant cells via animal NO synthase (NOS) or nitrate reductases and through nonenzymatic reactions. 摘要植物體可以通過(guò)依賴(lài)于類(lèi)似哺乳動(dòng)物的一氧化氮合成酶或硝酸還原酶的酶促合成途徑和非酶促合成途徑產(chǎn)生一氧化氮。
- There are decrease of ATP content,increase of LDH leakage,No production and NO Synthase(NOS)activity were obviously elevated during H/R. 缺氧/復氧損傷引起大鼠脊髓組織ATP含量減少和LDH漏出增多，NO生成和NOS活性明顯增加。
- NG-methyl-L-arginine (L-NMMA), the inhibitor of NO synthase, inhibited the production of NO and reversed the decrease of ATP and KBR. 一氧化氮合酶抑制劑NG-甲基-L-精氨酸（L-NMMA）可以抑制NO產(chǎn)生, 并使降低的肝細胞ATP含量和KBR得以恢復。
- Nitric Oxide(NO) mediate a number of physiological functions in hepatocytes,and the pathological processes of viral hepatitis NO synthase(NOS). 一氧化氮(NO)參與肝細胞的多項生理功能調節,參與病毒性肝炎的病理過(guò)程。
- Objective: The effects of nitr ic oxide(NO)and NO synthase inhibitor on endotoxin(ETX)-in- duced CGRP release from rat spinal cord in vitro were studied. 目的：探討一氧化氮（NO）及NO合成酶（NOS）抑制劑對內毒素引起的大鼠脊髓降鈣素基因相關(guān)肽（CGRP）釋放的影響。
- NO donor L Arg and ET receptor antagonist TAK 044 could alleviate the hepatic I/R injury in some degree, whereas NO synthase inhibitor L NAME aggravated the damage. NO供體L 精氨酸 (L Arg)與ET受體拮抗劑TAK 0 44在一定程度上可減輕肝I/R損傷 ,而NO合酶抑制劑L NAME進(jìn)一步加重了損傷。
- Because alveolar macrophages (AMs) expressed an abundance of inducible nitric oxide synthase (iNOS) and were important sources of NO in inflamed lung. 因為肺泡巨噬細胞表達豐富的誘生型一氧化氮合酶(inducible nitric oxide，iNOS)，是發(fā)生炎癥的肺組織中NO的重要來(lái)源。
- To study the mechanism of the dysfunction of platelet after coronary artery stent implantation (CASI),we observed the change of the product of nitric oxide (NO),activity of NO synthase (NOS) and L-Arginine transport before and after CASI. 通過(guò)觀(guān)察冠心病人PTCA支架植入術(shù)后血小板一氧化氮（NO）生成、NO合酶（NOS）活性和L-精氨酸（L－Arg）轉運的變化，探討PTCA支架術(shù)后血小板功能受損的機制。
- NO synthase inhibitor:NG-Nitro-L- arginine(L-NNA),NG-nitro-L-arginine methyl ester (L-NAME),NG-monomethyl-I-arginine acetate(L-NMMA),7-Nitroindazole had no effects on basel and the ETX-induced CGRP release from spinal cord in uitro. 各種NOS抑制劑L－NNA，L－NAME，L－NMMA和7－NI對離體大鼠脊髓CGRP的基礎釋放以及內毒素引起的CGRP釋放均無(wú)明顯影響。
- The role of DDAH is to break down modified amino acids (Asymmetric dimethylarginine (ADMA) and monomethyl arginine (L-NMMA)) that are produced by the body and hae been shown to inhibit NO synthase. DDAH的作用是破壞由體內產(chǎn)生的被修飾的氨基酸（不對稱(chēng)的二甲基精氨酸(ADMA)和一甲基精氨酸(L-NMMA)）并已證實(shí)它可以抑制NO的合成。
- Such phosphorylation results in endothelial NO synthase activation, which provides a novel explanation for the pleiotropic effects of statins that benefit the cardiovascular system. 如此磷酸化導致內皮NO合酶激活，為他汀類(lèi)藥物有益心血管系統的多效性提供了一個(gè)新的解釋。
- The up regulation of inducible nitric oxide synthase (iNOS) often negatively modulates myocardial function. 誘導型一氧化氮合酶的誘導表達往往導致心肌的收縮功能下降。
- The lecture induced no participation, when I asked questions the audience remained silent. 這次講演缺乏互動(dòng)，我提問(wèn)下面都沒(méi)人答言。
- Objective To detect the expression of inducible nitric oxide synthase (iNOS) in vestibule of guinea pig damaged by gentamicin. 目的檢測慶大霉素損傷后誘生型一氧化氮合酶在豚鼠內耳前庭中的表達。
- Results All the test results showed that M-PPC induced no cytotoxicity to Hela cell, and M-PPC had good biocompatibility in vivo and in vitro. 結果制備出M-PPC；M-P代無(wú)細胞毒性，植入白兔背部肌肉后，機體無(wú)任何炎癥反應。
- While the devices are much more complex than are TDMs, the process is much faster, induces no signal delay, creates no signal errors. 然而ADM比TDM（時(shí)分復用）復雜得多，處理速度快得多，沒(méi)有信號延時(shí)，沒(méi)有信號誤碼。
