To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants tails. 對于不同狀態(tài)的染色質(zhì)，核小體中會(huì )組裝人相應的組蛋白變體，并且各種組蛋白變體的尾部也能發(fā)生多種修飾。
But enough evidence has accumulated to prove that some proteins can in fact copy themselves and that variants of PrP are essential players in spongiform encephalopathies. 但是充足的證據證明，某些蛋白質(zhì)的確可以自我復制，且普恩蛋白變體在海綿狀腦病上扮演了重要角色。
