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- Recently, with using of whole genome genotyping and linkage analysis, some chromosome regions have been related to human dermatoglyphic patterns. 特別是最近幾年，通過(guò)全基因組基因分型和連鎖分析，在染色體上得到了一些和膚紋特征相關(guān)的基因候選區域。
- Another important method of linkage analysis is the Affected Sib Pair (ASP). 連鎖分析的另一種重要統計方法是生病同胞對法(ASP)。
- Methods The parameter linkage analysis of the small pedigree data was used. 方法運用小家系資料連鎖分析參數的方法。
- Objective: Two recent genome wide association (GWA) studies have revealed novel loci for type 1 diabetes (T1D), a common multifactorial disease with a strong genetic component. 近日，兩個(gè)知名的基因組協(xié)會(huì )研究發(fā)現新的基因位點(diǎn)的1型糖尿?。═1D）。
- Keywords nonsyndromic deafness;maternal inheritance;mtDNA mutation;whole genome?wide screen;linkage analysis; 非綜合征耳聾;母系遺傳;線(xiàn)粒體突變;全基因組掃描;連鎖分析;
- RFLP Linkage Analysis and deletion analysis in one family with BMD and two families with DMD. 一個(gè)BMD和二個(gè)DMD家系的RFLP連鎖分析和缺失分析
- This information is valuable both as a prelude to linkage analysis, which generally assumes Mendelian transmission. 這一信息有利于進(jìn)一步所做的連鎖分析。
- Objective To identify the disease locus in X-linked retinitis pigmentosa (RP) families using genetic linkage analysis. 目的應用遺傳連鎖分析方法對X連鎖型視網(wǎng)膜色素變性家系進(jìn)行分析,定位其致病基因的所在位點(diǎn)。
- Selection is practically ubiquitous during marker-QTL linkage analysis with an experimental population. 從實(shí)際角度看，選擇在用于標記-QTL連鎖分析的實(shí)驗群體中是較普遍存在的。
- Objective To identify the disease locus in X-linked retinitis pigmentosa(XLRP) families using genetic linkage analysis. 目的應用遺傳連鎖分析方法對X連鎖型視網(wǎng)膜色素變性家系進(jìn)行分析,確定其致病基因的所在位點(diǎn)。
- Meanwhile,the method of gene linkage analysis and that of using oligonucleotide probe are compared. 同時(shí)將基因的連鎖分析法與寡核苷酸法進(jìn)行了比較。
- This STR linkage analysis can identify the molecular defect of PWS cases quickly and accurately. STR連鎖分析是一種可準確診斷PWS并明確其分子缺陷類(lèi)型的好方法；
- But no pathogenetic gene has been cloned. To refine the location of CMN, we had research on a Chinese pedigree of CMN through genescan and linkage analysis. 我們擬應用基因組掃描技術(shù)，通過(guò)連鎖分析對一個(gè)來(lái)自于浙江溫州的CMN家系進(jìn)行相關(guān)致病基因的染色體定位研究。
- Objective To study the clinical application value of genetic linkage analysis for bronchial asthma with two STRs-D5S436 and D5S658. 目的探索短串聯(lián)重復序列-D5S436和D5S658在支氣管哮喘家系連鎖分析中的應用價(jià)值。
- Haplotype and linkage analysis indicate that the Ashkenazi haplotypes is not associated with HMPS in Singapore Chinese families,which suggests genetic heterogeneity. 單倍型及遺傳連鎖分析提示,Ashkenazi單倍型與華人HMPS無(wú)關(guān),兩者存在遺傳背景的差異性。
- The two-locus, non-parametric linkage analysis (NPL), maximum LOD score and transmission/disequilibrium test (TDT) with GENEHUNTER program were used in this study. 統計采用GENEHUNTER軟件包兩點(diǎn)非參數連鎖（NPL）分析、計算優(yōu)勢對數記分(Lod)值及傳遞不平衡檢驗（TDT）。
- Genome Wide Loss of Heterozygosity in Primary Nasopharyngeal Carcinoma 鼻咽癌全基因組雜合性缺失分析
- First half focuses on human genetics and molecular biology, covering fundamentals of pedigree analysis, linkage analysis, molecular cloning, and gene analysis as well as ethical/ legal issues, all in the context of an auditory disorder. 前半段會(huì )著(zhù)重于人類(lèi)遺傳學(xué)與分子生物學(xué)，涵蓋家族系譜分析、鎖分析、子選殖、因分析與道德法律議題的基礎概述，并且皆以聽(tīng)覺(jué)系統疾病為例來(lái)說(shuō)明。
- The flood cut a wide swath in this area. 洪水席卷了這一地區，滿(mǎn)目一片瘡痍。
- Simulation study and real data analysis were performed using SAS/IML software, and the validity and practicability of Bayesian method in genetic linkage analysis were thus verified. 用編制的SAS/IML程序進(jìn)行了模擬研究和實(shí)例分析，驗證了貝葉斯方法在遺傳連鎖分析中的有效性和實(shí)用性。
