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- 目的利用Bac-to-Bac桿狀病毒表達系統,將人堿性成纖維細胞生長(cháng)因子(human basic fibroblast growth factor,hbFGF)基因進(jìn)行表達,并檢測重組蛋白的特異性及生物學(xué)活性。Objective Bac-to-Bac baculovirus expression system was used to obtain biologically active recombinant human basic fibroblast growth factor(hbFGF) in insect cells.
- 目的 比較類(lèi)風(fēng)濕關(guān)節炎 (rheumatoidarthritis,RA)與骨關(guān)節炎 (osteoarthritis,OA)成纖維樣滑膜細胞 (fibroblast likesynoviocytes,FLS)蛋白酪氨酸磷酸化狀態(tài)的差異 ;Objective To evaluate the change of tyrosine phosphorylation status in rheumatoid arthritis fibroblast like synoviocytes (RA FLS),compared with osteoarthritis (OA) FLS;
- 目的應用細胞增生指標核仁組成區相關(guān)嗜銀蛋白(argyrophilic nucleoar organ-izer regions granules,AgNORs),觀(guān)察兔眼濾過(guò)道成纖維細胞(fibroblast,Fb)增生規律及三氧化二砷(arsenic trioxide,As2O3)的抗增生作用。Objective To investigate the proliferative regularity of fibroblasts(Fb) in the filtrate passageway of rabbit and observe the effect of arsenic trioxide(As2O3) on inhibiting the proliferation of Fb by taking argyrophilic nucleoar organizer regions granules (AgNORs) as a proliferative index. Methods Forty-eight rabbits were divided into experimental and control group randomly.
