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- Dextromethorphan hydrobromide and ibuprofen capsules were determined by HPLC. 用HPLC測定復方膠囊中右美沙芬、布洛芬的溶出度。
- It is practicable to apply the method for the assay of Dextromethorphan Hydrobromide and Guaifenesin for Suspension. 結論：方法準確、靈敏、可靠,適用于氫溴酸右美沙芬愈創(chuàng )甘油醚干混懸劑的含量測定。
- Dextromethorphan hydrobromide sustained-release matrix pellets wereproduced by extrusion-spheronisaion. 氫溴酸右美沙芬骨架緩釋微丸的制備采用擠出滾圓法。
- Objective To evaluate the stability of the controlled-release pellets of dextromethorphan hydrobromide. 目的考察氫溴酸右美沙芬控釋膠囊的穩定性。
- Objective: To prepare the dextromethorphan oral sustained-release suspensions and study the in-vitro release kinetics. 目的:制備右美沙芬樹(shù)脂口服緩釋混懸液,并考察其釋藥特性。
- HPLC method for determination of guaifenesin and dextromethorphan hydrobromide in dispersibletablets was established. 建立了HPLC法測定愈美分散片中愈創(chuàng )木酚甘油醚和氫溴酸右美沙芬的含量。
- Conclusion: Dextromethorphan has synergism to Methadone and reduce its dosage during detoxification. 結論美沙芬對美沙酮有協(xié)同作用,可以減少脫毒治療時(shí)美沙酮的用量。。
- Objectives: To examine the effect of dextromethorphan in the treatment of heroin withdrawal symptoms by Methadone. 目的研究美沙芬在美沙酮治療海洛因戒斷癥狀中的作用。
- Methods Dextromethorphan Sustained-Release capsules of lasting antitussive were observed by acid citric induced cough model of guinea pig. 目的觀(guān)察氫溴酸右美沙芬緩釋膠囊的鎮咳作用及鎮咳作用時(shí)間。
- Objective:To research the preparation, control in quality and stability of Paracetamol pseadoephedrine Hydrochloride and Dextromethorphan Hydrobromide dispersible tablet. 目的:研究氨芬偽麻美芬片的制備并對其質(zhì)量進(jìn)行控制和穩定性考察。
- Dextromethorphan is a synthetic compound.Dextromethorphan has been abused and is claimed to be habit forming but has not been reported to produce physical dependence. 氫溴酸右美沙芬和其代謝物右啡烷的止咳作用主要是由于與中央神經(jīng)系統的非鴉片樣藥感受器官結合。
- Here the measurement of 50% inhibitory concentration (IC50) for CYP2D6 with non-inhibitor (dextromethorphan) and inhibitor (quinidine) using SPR biosensor is demonstrated. 因此在此以CYP2D6為例，測量50%25抑制濃度來(lái)比較非抑制性藥物和抑制性藥物的差別。
- Method: A randomized, single-hlind and controlled study was carried out, dextromethorphan plus Methadone were applied in study group (N=25) and only Methadone in control group. 方法采用隨機單盲對照試驗設計,試驗組25例采用美沙芬與美沙酮合并用藥,對照組25例僅用美沙酮。
- Methods:Using orthogonal designed compound dextromethorphan syrup as a model drug.The grade point synthesized was introduced to quantify the stability characteristics. 方法:以復方氫溴酸右美沙芬糖漿為模型藥物,采用正交設計,在評價(jià)指標中引入綜合評分來(lái)量化穩定性和口感,考察不同處方、工藝對此指標的影響程度。
- Their duration of action was longer than that of lidocaine.Co-administration of dextromethorphan and its metabolites produced additive effect on sciatic nerve blockade. 而且當右美沙芬、右啡烷、甲氧基嗎啡喃與利多卡因合并給予在大白鼠周邊的坐骨神經(jīng)阻斷上亦具有加成作用。
- HPLC method with fluorescence detection for determination of dextromethorphan (1) and its active metabolite, dextrorphan (2) in human plasma was presented. 建立了簡(jiǎn)便、準確、靈敏的反相高效液相色譜-熒光檢測法測定人血漿中右美沙芬和活性代謝物去甲右美沙芬的血藥濃度。
- OBJECTIVE: To establish a LC/MS method for the determination of dextromethorphan in human plasma and to study its pharmacokinetics in healthy Chinese volunteers. 目的:建立以液/質(zhì)聯(lián)用法測定人血漿中右美沙芬濃度的方法,并研究其在健康人體的藥動(dòng)學(xué)。
- Methods:The dextromethorphan oral sustained-release suspensions were prepared using ion exchange resin as a carrier,and followed by coating with ethylcellulose using the Wurster fluid bed process. 方法:采用離子交換樹(shù)脂為載體制備含藥樹(shù)脂微粒,用流化床進(jìn)行包衣,并通過(guò)處方優(yōu)化制備右美沙芬樹(shù)脂口服緩釋混懸液。
- The bioequivalence and pharmacokinetics of domestic dextromethorphan hydrobromide extended release suspension was investigated in 18 healthy man volunteers, according to randomized crossover design. 在18名男性健康受試者中研究國產(chǎn)右美沙芬緩釋混懸液的藥物動(dòng)力學(xué)特性及生物等效性。
- The investigators randomized 230 adults diagnosed with acute bronchitis to receive either azithromycin or vitamin C for 5 days, along with liquid dextromethorphan and an albuterol inhaler. 研究者把230名診斷為急性支氣管炎的成年患者隨機分為兩組，接受連續5天的阿齊黴素或維生素C治療，同時(shí)給予脂溶性右甲嗎喃和一種沙丁胺醇吸入劑。
