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- By contrast, the oncogenic variant spontaneously forms dimers that are constitutively active. 與此不同，致癌突變體自發(fā)形成有持續活性的二聚體。
- NF-[kappa] B has been demonstrated to be constitutively active in smooth muscle cell (SMC), and it is responsible for the expression of several genes after SMC injuring. 其在血管平滑肌細胞中一直是活躍的，在平滑肌細胞損傷后開(kāi)始表達引起上述的多種基因的表達[2-4]。
- In this study, we found that over expression of STAT1 in LL2 cells that express constitutively active STAT3 may restore innate immunity but did not inhibit the tumor formation, especially in vivo. 在本研究中，我們發(fā)現，在表現持續活化態(tài)STAT3的腫瘤細胞中，給予持續活化態(tài)STAT1的過(guò)度表現，可能回復宿主的先天性免疫系統，然而在動(dòng)物體內腫瘤的生長(cháng)不會(huì )被抑制。
- Constitutively activated STAT3 is found in many cancers,including melanoma,breast cancer,head and neck cancer,implying the critical role of STAT3 in tumorgenesis. 研究表明，STAT3的持續激活與許多腫瘤和癌癥相關(guān)，如黑色素瘤、骨髓瘤、急慢性白血病、頭頸癌、乳腺癌、前列腺癌、小細胞癌等。
- Constitutive activation of STATS was present in BEL-7402 cells. 肝癌細胞中Wnt異常信號轉導途徑對細胞增殖及遷移的影響
- Keywords Yeast,CXCR4, constitutively active,agonist,conformaitonal change; 酵母;CXCR4;組成性活性;激動(dòng)劑;構象變化;
- The orient has been playing an active role in the world economy. 亞洲一直在世界經(jīng)濟中發(fā)揮積極作用。
- He is an active member of the school's stamp club. 他是學(xué)校集郵俱樂(lè )部的一名活躍會(huì )員。
- An active volcano may explode at any time. 活火山隨時(shí)都有可能爆發(fā)。
- Is it wise to engage in active sports at your age? 我這樣的年紀積極參加體育活動(dòng)是否明智？
- She was active as a left-winger in the party. 她是黨內積極的左翼分子。
- He was very active and rode down several horses. 他勁頭很大，一連騎了好幾匹馬。
- Similarly, the constitutive activation of signaling cascades that stimulate cell growth has a profound impact on anabolic metabolism. 類(lèi)似的，刺激細胞生長(cháng)組成性激活的信號傳遞對同化代謝具有重大的影響。
- She plays an active part in local politics. 她積極參與地方政治活動(dòng)。
- The steel market will continue to be active. 鋼材市場(chǎng)將會(huì )繼續保持活躍。
- An active volcano may erupt at any time. 活火山隨時(shí)可能?chē)姲l(fā)。
- The mutant DNA miscoded a single amino acid. 突變體脫氧核糖核酸誤編了一個(gè)氨基酸密碼。
- He was disabled when on active service. 他在戰斗中受傷致殘。
- Ms. Brown is active in the party. 布朗女士在晚會(huì )上很活躍。
- Gangs of disaffected mutant teenagers. 一群對現實(shí)不滿(mǎn)、形容怪異的年輕人
