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- Methods The C ring in sinomenine was modified. 方法以青藤堿為先導物，對C環(huán)進(jìn)行結構改造。
- AIM To study the preparation and stability of sinomenine liposomes. 目的:優(yōu)選青藤堿脂質(zhì)體的制備方法,并研究其穩定性。
- Aim To provide basic data for the synthesis of new sinomenine derivatives. 目的為定向設計合成高效低毒的新一代青藤堿類(lèi)藥物提供線(xiàn)索。
- Objective: To prepare sinomenine gel and study its skin penetration in vitro. 目的:制備青藤堿凝膠劑,研究其透皮滲透性能。
- Results Sinomenine could induce apoptosis o f synoviocytes in CIA rats. 結果青藤堿組CIA大鼠滑膜細胞的凋亡數明顯增加。
- Aim Io provide basic data for the synthesis of new sinomenine derivatives. 摘要目的為定向設計合成高效低毒的新一代青藤堿類(lèi)藥物提供線(xiàn)索。
- OBJECTIVE: To develop a preparation and quality control method for sinomenine gel. 目的:探討青藤堿凝膠的制備及質(zhì)量控制標準。
- Objective:To prepare Sinomenine hydrochloride-loaded bovine serum albumin microspheres(SM-BSA-MS). 目的:制備具有緩釋作用的鹽酸青藤堿牛血清白蛋白微球。
- PIA in rats was chosen as a RA model to investigate Sinomenine and MTX on theprevention of RA. 本研究以 PIA 大鼠為研究對象,探討青藤堿和 MTX 對 RA 的預防作用。
- Objective: To investigate the activities of transdermal penetration of sinomenine liposome patch. 摘要 目的：研究青藤堿脂質(zhì)體貼劑的經(jīng)皮滲透行為。
- OBJECTIVE:To develop a preparation and quality control method for sinomenine gel. 目的:探討青藤堿凝膠的制備及質(zhì)量控制標準。
- METHODS:Sinomenine gel was prepared with carpol971as base.TLC and UV were employed for identification of sinomenine. 方法:以卡波姆為輔料制備青藤堿凝膠劑,采用薄層色譜法及紫外分光光度法鑒別青藤堿;
- The anti-inflammatory effect of sinomenine was assessed in the treatment of the rat models. 方法制備大鼠佐劑性關(guān)節炎模型,觀(guān)察青藤堿的作用。
- Conclusions:The combined extraction is beneficial to improve the extraction of sinomenine. 結論:青風(fēng)藤與延胡索混合提取有利于提高青藤堿的提取率。
- Objective To prepare sinomenine hydrochloride transfersomes and evaluate their qualities. 目的制備鹽酸青藤堿傳遞體,并進(jìn)行質(zhì)量評價(jià)。
- Objective: To establish an HPLC method for the determination of entrapment efficiency of sinomenine liposomes. 目的:建立青藤堿脂質(zhì)體包封率的測定方法。
- The extrct was purified by activity carbon,and then the product of sinomenine was obtained by recrystallization. 以苯為溶劑采用超聲法對青風(fēng)藤根進(jìn)行提取,超聲提取物經(jīng)活性碳脫色純化和重結晶即可得產(chǎn)品青藤堿。
- Steep main peak, the North-South gradient smaller low, Sinomenine with weeds, Exotic perennial habitat here. 主峰陡峭，北高南低坡度較小，野草青藤橫生，珍禽異獸常年棲息于此。
- The therapeutic effect of sinomenine on rheumatoid arthritis may be related to its inhibition to secretion of IL-12 in DCs. 青藤堿的抗類(lèi)風(fēng)濕作用可能與其抑制樹(shù)突狀細胞分泌白細胞介素12有關(guān).
- A method for the quantitive determination of sinomenine in “Sinomenium” was de veloped by double waveleath HPTLC densitometricsanning. 采用高效薄層色譜雙波長(cháng)掃描法對青風(fēng)藤中青藤堿的含量進(jìn)行了測定。
