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- Pm Dr. Jiong Wu, Cell Signaling Technology Phospho-Tyrosine Kinase Specific Antibodies: From Targets to Therapeutics. 磷酸化酪氨酸激酶特異性抗體:從靶標到治療的發(fā)展。
- Abstract Abstract In recent years, small G proteins have become an intensively studied group of regulatory GTP hydrolyses involved in cell signaling. 摘要 近年來(lái)，小G蛋白的調控途徑已經(jīng)成為人們研究細胞信號轉導過(guò)程的熱點(diǎn)問(wèn)題。
- This process is used in a wide range of biochemical reactions, including allergic responses and cell signaling in cancer. 該處理為生物化學(xué)反應寬廣領(lǐng)域中采用，包括過(guò)敏反應和癌癥中細胞信號傳導等。
- Protein nitration will induce the changes of protein catalytic activities, cell signaling and cell skeletal structure,and lead to relevant pathological events. 蛋白質(zhì)硝化將會(huì )直接影響蛋白質(zhì)的催化活性、細胞信號傳遞和細胞骨架結構,導致相關(guān)病癥的發(fā)生發(fā)展。
- He did his postdoctoral training on apoptosis at the Weizmann Institute of Sciences in Israel, and on cancer cell signaling at the Harvard Medical School in the United States. 1997年赴以色列魏茲曼研究所接受博士后訓練，從事細胞凋亡或程序性細胞死亡的研究；2000年進(jìn)入美國哈佛大學(xué)醫學(xué)院繼續博士后研究工作，主要研究領(lǐng)域為腫瘤細胞信號傳導。
- ABSTRACT In the quantities of regulation mechanisms of cell signaling transduction, the phosphorylation and dephosphorylation of proteins are of importance. 中文摘要 在細胞信號轉導的眾多調節過(guò)程中，蛋白質(zhì)的磷酸化與去磷酸化是十分重要的環(huán)節，特定細胞蛋白質(zhì)酪氨酸殘基發(fā)生磷酸化是細胞信號轉導的重要調節機制，它是細胞間通信、細胞生長(cháng)和增殖、細胞周期調控、分化、惡性腫瘤的發(fā)生和轉移、神經(jīng)傳導、血管形成、胚胎形成和許多遺傳病及后天人類(lèi)疾病的一個(gè)關(guān)鍵步驟。
- Protein nitration will induce the changes of protein catalytic activities, cell signaling and cell skeletal structure, and lead to relevant pathological events. 蛋白質(zhì)硝化將會(huì )直接影響蛋白質(zhì)的催化活性、細胞信號傳遞和細胞骨架結構，導致相關(guān)病癥的發(fā)生發(fā)展。
- Cell signal transduction is major research field in life science,and 10 Nobel Prizes in medicine and physiology were awarded in this field. 細胞信號轉導是目前生命科學(xué)研究的一個(gè)重要內容,至今已獲得10次諾貝爾生理與醫學(xué)獎,說(shuō)明了它的重要性。
- PIP_2 is a pivotal regulator in cell signaling pathway. DAG and IP_3, which are generated from PIP_2 hydrolysis by PLC, act as second messengers to activate PKC and induce intracellular Ca release, respectively. PIP_2是細胞信號轉導通路中的關(guān)鍵調節因子，經(jīng)磷脂酶C(PLC)水解后可生成DAG及IP_3，二者可作為第二信使，分別激活PKC與促使細胞內鈣庫釋鈣。
- Tyrosine protein kinase is one of the key kinases in cell signal transduction,which plays an important role in cell growth,development and functional regulation. 酪氨酸蛋白激酶是細胞信號轉導的主要信號酶之一,對細胞的生長(cháng)、發(fā)育與功能調控起著(zhù)重要的作用。
- This paper reviews the close connection of senescence and pertinent pathological changes with cell signal transductions which have brought obstacles or abnormity. 概述了衰老及相關(guān)病變與細胞信號轉導障礙或異常的密切關(guān)系。
- Cell signaling Cells communicate with one another in multicellular organisms using extracellular signaling molecules or hormones . 細胞信號轉導 在多細胞生物中，細胞用胞外信號分子或激素彼此進(jìn)行交流。
- Cell cell interactions in the epididymis are mediated by adhering junctions which are necessary for cell adhesion and tight junctions which form the blood epididymal barrier. 附睪細胞間相互作用是由粘著(zhù)連接介導的,這種粘著(zhù)連接在形成血附睪屏障的細胞粘著(zhù)和緊密連接中必不可少。
- Experimental studies have showed its effects in inhibiting metastases,apoptotic induction,cell signal transduction and prevention of liver carcinogenesis. 實(shí)驗研究發(fā)現其具有抗轉移、誘導腫瘤細胞凋亡、影響細胞信號轉導以及預防肝癌發(fā)生的作用。
- The sun's oltra`` ultraviolet rays react with skin cell cells to produce vitamin D. 太陽(yáng)的紫外線(xiàn)光束與皮膚細胞發(fā)生反應來(lái)產(chǎn)生維他命D。
- While ACTM gene is well known to code a-actinin 1 protein which involes in cell skeleten and cell signals. ACTN1編碼輔肌動(dòng)蛋白1，則是公認的與細胞骨架和細胞通訊有關(guān)的基因。
- Objective To explore the biodynamic properties of bone marrow cells and the relation with cell cell interaction in radiation injury mice. 目的了解放射損傷條件下骨髓細胞的生物力學(xué)特性及與細胞間相互作用的關(guān)系。
- Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors. 受體酪氨酸蛋白激酶是細胞信號轉導進(jìn)行的關(guān)鍵信號酶,在生長(cháng)因子調控細胞生長(cháng)、發(fā)育與功能的過(guò)程中起著(zhù)重要的生理作用。
- Two important cell signal pathways, JAK-STAT pathway and MAPK pathway, transfer the signals between regulators and hematopoietic relative genes. 兩條主要的細胞信號轉導通路，JAK-STAT通路和MAPK通路，介導調節調節因子對造血相關(guān)基因的活性調控。
- Wireless signal field test aimed at measuring and evaluating indoor cell signal distribution system, an outdoor macrocell signal interference with other systems in the indoor signal distribution. 無(wú)線(xiàn)信號場(chǎng)強測試的目的在于測量和評估室內分布系統各小區信號、室外宏蜂窩信號、其他系統干擾信號在室內分布的情況。
