We developed a general computational strategy for creating these protein structures that incorporates full backbone flexibility into rotamer-based sequence optimization. 我們開(kāi)發(fā)了一種通用的計算策略，用于創(chuàng )造這些能將完整的骨架彈性整合進(jìn)最優(yōu)化螺旋異構體序列的蛋白質(zhì)。
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