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- A method was developed for determination of adenylate cyclase(AC) and cAMP phosphodiesterase(PDE) specific activities by radioisotopic assay. 本文報道腺苷酸環(huán)化酶(AC)和環(huán)腺苷酸磷酸二酯酶(PDE)比活力的放射性同位素測定法。
- Effects of narcotics on adenyl cyclase and phosphodiesterase activity in rabbit bronchial smooth muscle. 常用麻醉性鎮痛藥對家兔支氣管平滑肌腺苷酸環(huán)化酶和磷酸二酯酶活力的影響
- Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. 磷酸二酯酶8B基因變異體與血清TSH水平和甲狀腺功能有關(guān)。
- Many men in their reproductive years are now using phosphodiesterase type 5 inhibitors. 目前許多生育期男性在服用磷酸二酯酶5抑制劑。
- Inhibitor of cyclic adenosine 3’,5’-monophosphate phosphodiesterase and topoisomerase ITopo I). 抑制環(huán)腺苷3’,5’-一磷酸鹽磷酸二酯酶和拓撲酶I。
- I also use a medicine called Trental or Pentoxifylline as a phosphodiesterase inhibitor. 我也使用磷酸二酯酶抑制劑如巡能泰或己酮可可堿進(jìn)行治療。
- ED treatment has changed fundamentally since phosphodiesterase type 5 inhibitor(PDE5-I) came into clinizal use. 自從5型磷酸二酯酶抑制劑(PDE5-I)出現后,ED的治療發(fā)生了革命性的變化。
- Phosphodiesterase 3 inhibitor attenuates cough response in a sensitized guinea pig model. 中國病理生理雜志，第二，2007年，in press。
- Attempts have been made to know the statws quo of the phosphodiesterase inhibitor clinical practice in recent years. 了解磷酸二酯酶抑制劑近年來(lái)的臨床應用情況,并對其作用機制進(jìn)行分析,為進(jìn)一步的開(kāi)發(fā)應用提供依據。
- This same enzyme, phosphodiesterase type 5, also limits blood flow by contracting the muscles around blood vessels. 同一種酶，5型磷酸二酯酶也通過(guò)收縮血管壁平滑肌減少血流。
- PURPOSE: Phosphodiesterase type 5 inhibitors are the first choice therapy in the treatment of erectile dysfunction. 目的：磷酸二酯酶5抑制劑是治療勃起功能障礙的首選用藥。
- Benzylisoquinoline compounds antagonized calmodulin ( CaM ) to inhibit the activity of CaM-dependent cyclic nucleotide phosphodiesterase ( CaM-PDE ) . 芐基異喹啉類(lèi)化合物拮抗鈣調素(CaM),對環(huán)核苷酸磷酸二酯酶(CaM-PDE)產(chǎn)生抑制作用。
- Sildenafil citrate is a phosphodiesterase type 5 (PDE5) inhibitor used clinically for the treatment of male erectile dysfunction. 枸櫞酸西地那非是磷酸二酯酶-5(PDE5)的抑制劑，臨床用來(lái)治療勃起機能障礙。
- And one of the things were looking at is specific phosphodiesterase inhibitors to block the endotoxin or LPS-stimulable TNF. 目前正在做的一項工作是用特異性磷酸二酯酶抑制劑來(lái)阻斷內毒素或LPS脂多糖刺激TNF的產(chǎn)生。
- Saleheen D,Bukhari S,Haider SR,et al.Association of phosphodiesterase 4D gene with ischemic stroke in a pakistani population[J].Stroke,2005,36:2275. 李才明;張成;張鴻煉;等.;磷酸二酯酶4D基因與缺血性腦卒中的遺傳易患性研究[J]
- The authors have done the research by consulting the relative domestic phosphodiesterase inhibitor literature published in recent years. 查閱近年來(lái)國內有關(guān)磷酸二酯酶抑制劑的文獻資料。
- Objective:To observe the effect of Guizhi Decoction (GZD) on adenyl cyclase (AC) and phosphodiesterase (PDE) activities in hypothalamus of rat models of fever and hypothermia. 目的 :觀(guān)察桂枝湯對發(fā)熱和低體溫模型大鼠下丘腦中腺苷酸環(huán)化酶 (AC)和磷酸二酯酶(PDE)活性的影響。
- Benzylisoquinoline compounds antagonize calmodulin (CaM) and inhibit the activity of cyclic nucleotide phosphodiesterase which is CaM-dependent (CaM-PDE) . 芐基異喹啉類(lèi)化合物拮抗鈣調素(CaM)并抑制依賴(lài)CaM的環(huán)核苷酸磷酸二酯酶(CaM-PDE)的活力;
- Phosphodiesterase 4(PDE 4),which specifically decomposes cAMP,is mainly distributed in various inflammatory cells and promotes exacerbation of inflammation. 磷酸二酯酶 (PDE- 4 )主要分布于各類(lèi)炎性細胞 ,能專(zhuān)一性水解環(huán)腺苷酸 (c AMP) ,促進(jìn)炎癥的發(fā)展。
- The yeast Saccharomyces cerevisiae contains two genes, PDE1 and PDE2, whichencode a low-affinity and a high-affinity cAMP phosphodiesterase, respectively. 釀酒酵母本身具有兩個(gè)編碼環(huán)腺苷酸(cAMP)磷酸二酯酶的基因PDE1和PDE2。 它們分別編碼低親和力的cAMP磷酸二脂酶Pde1和高親和力的cAMP磷酸二脂酶Pde2。
