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- 在NCBI進(jìn)行Blast P搜索結果顯示豬CTSD氨基酸結構中含有Asn(Asparagine,天門(mén)冬酰胺)結構域,與天冬氨酸蛋白酶3D結構同源性高達99.7%,具有真核生物天冬氨酸蛋白酶的典型結構。The deduced 410 amino acid of CTSD was predicted to contain an Asn(Asparagine) domain which was the representative structure of lysosomal aspartic proteinase by blast in NCBI,and three-dimentional structure of porcine CTSD showed 99.7%25 alignment to that of mammalian CTSD.
- 在密碼子應用上,第一位為A的氨基酸(賴(lài)氨酸lysine[AAA]、天冬酰胺asparagine[AAY]、絲氨酸serine[AGR])使用頻率較高,這三種氨基酸占整個(gè)蛋白質(zhì)氨基酸的30.59%(Lys9.95,Asn 9.52,Ser 11.12)。The most common amino acids and codons are lysine[AAA, asparagines[AAY] and serine[AGR]. The average content of AAA, AAY, AGR is 9.95%25, 9.52%25 and 11.12%25 respectively.