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- Testosterone and dihydrotestosterone can only be effective through binding to the androgen receptor encoded by gene AR. 雙氫睪酮和它的前體睪酮都要是通過(guò)雄激素受體(AR)作用于它們的靶器官來(lái)發(fā)揮其生物學(xué)效應。
- The androgen receptor(AR)belongs to the steroid receptor family,which is a part of the large nuclear receptor superfamily. 雄激素受體(AR)屬于核受體超家族中的類(lèi)固醇受體。
- Objective To explore the relationship between the CAG mirosatellite in androgen receptor(AR)gene and the stage and grade of prostate cancer(PC). 目的研究雄激素受體(AR)基因三核苷酸CAG微衛星多態(tài)性與前列腺癌(PC)分期和分級的關(guān)系,探討其與腫瘤生物學(xué)特性的相關(guān)性。
- To study the clinical features and the role of androgen receptor ( AR ) and insulin receptor ( IR ) in auto-para endocrine control of asymmetric polycystic ovaries ( PCO ). 探討不對稱(chēng)性多囊卵巢(PCO)的臨床特點(diǎn)及雄激素受體(AR)和胰島素受體(IR)在其發(fā)病機制中的作用。
- Androgen Insensitivity Syndrome (AIS) is an X-linked disorder of male sexual differentiation, caused by an absent or dysfunctional androgen receptor (AR). 雄性激素不敏感綜合征(AIS)是雄性激素受體(AR)缺陷引起的雄性性發(fā)育失常,是一種X染色體連鎖疾病。
- Our aim was to examine the role of the sex hormone-binding globulin (SHBG) and androgen receptor (AR) gene polymorphisms, in the phenotypic expression of PCOS. 目的 研究性激素結合球蛋白(SHBG)和雄激素受體(AR)基因多態(tài)性在PCOS中的表型表達。
- Spinal and bulbar muscular atrophy (SBMA) is an adult form of X-linked motor neuron disease caused by an expansion of a CAG repeat sequence in the first exon of the androgen receptor (AR) gene. 脊髓延髓肌萎縮癥(SBMA)是雄激素受體(AR)基因的CAG重復序列擴增引起的X連鎖運動(dòng)神經(jīng)元病。
- Estrogen receptor(ER) and Androgen receptor(AR) assays were performed with fluorescent histochemical method in 89 cases of bladder carcinoma.77 cases were followed up for at leazt six years. 采用熒光組織化學(xué)法測定了89例膀胱移行細胞癌雌雄激素受體的表達,獲長(cháng)期隨訪(fǎng)的77例中有32例復發(fā),復發(fā)率為41。
- Androgen Receptor in liver cancer progression. Oncogene or tumor suppressor? 男性激素受體與肝癌:致癌或是抑癌基因?
- The key is something called a selective androgen receptor modulator, or SARM. 關(guān)鍵是所謂選擇性雄激素受體調節劑,或行動(dòng)情報處。
- BY THE MODULATION OF ANDROGEN RECEPTOR COFACTORS, IS IT POSSIBLE THAT PHYTOESTROGEN MAY ACT AS PHYTOANDROGEN ? 在雄性激素受體的輔助因子存在下,植物性雌激素是否會(huì )有雄性激素之表現?
- Method Androgen receptor in 112 hypertensive men and 120 normotensive men was measured by means of flow cytometry. 方法 運用流式細胞術(shù)檢測112例男性高血壓患者(高血壓組)及120例健康男性體檢者(對照組)雄激素受體的狀態(tài)。
- It is caused by mutations in the androgen receptor gene,resulting in decrease or absence of normal andrognen receptor. 因為發(fā)育異常的睪丸存在惡變可能,目前普遍認為應該首選睪丸切除術(shù),但在手術(shù)時(shí)機的選擇上還存在著(zhù)很多爭議。
- Androgen and exercise can regulate the capacity and affinity of androgen receptor in skeletal muscle. 雄激素和運動(dòng)對骨骼肌中雄激素受體具有調節作用;
- The gene affects the androgen receptor, a protein that helps activate male hormones. 這種基因影響男性荷爾蒙接受器,這是一種幫助激活男性荷爾蒙的蛋白質(zhì)。
- Androgen receptor belongs to the nuclear receptor superfamily and is a ligand-dependent transcription regulator, which can be activated by androgen. 雄激素受體屬于核受體超家族,為配體依賴(lài)性基因轉錄因子,與雄激素結合后被激活。
- The authors develop a protein-fragment complementation assay that specifically evaluates androgen receptor ligands in the context of signal activation. 作者開(kāi)發(fā)一種蛋白質(zhì)片段互補分析;具體評價(jià)激素受體配體的背景信號激活.
- Conclusions: No significant increased length of (CAG)n repeats in androgen receptor gene is found for severe oligozoospermia or azoospermia patients. 結論:無(wú)精或嚴重少弱精癥患者與雄激素受體基因(CAG)n重復數的沒(méi)有關(guān)系。
- Objective: To study the relationship between androgen receptors(AR) and estrogen receptors(ER) in cells and nuclei of prepuce in patients with hypospadias and the severity of hypospadias. 目的:探索先天性尿道下裂與陰莖皮膚細胞雄激素受體(AR)、雌激素受體(ER)的表達及細胞核內的聚集的關(guān)系。
- Androgen Insensitivity Syndrome (AIS) is an X-linked disorder of male sexual differentiation, caused by a defective or absent androgen receptor. 雄性激素不敏感綜合征是一種X染色體連鎖的男性性發(fā)育異常疾病,由雄性激素受體缺陷或缺失引起。