We have summarized a total of 48 mutations in the ADAR gene with DSH by previous reports and speculated that the mutation hotspots of ADAR gene might be located in the tRNA-specific and double-stranded RNA adenosine deaminase (ADEAMc) domain.

 
  • 到目前為止,共發(fā)現48個(gè)DSH的A-DAR基因突變,推測ADAR基因的突變熱點(diǎn)可能位于A(yíng)DEAMc區域。
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